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毛霉菌病:一种使新型冠状病毒肺炎大流行复杂化的流行病。

Mucormycosis: An Epidemic Complicating the COVID-19 Pandemic.

作者信息

Khade Shalaka, Nalwa Aasma, Rao Meenakshi, Aggarwal Divya, Sharma Vidhu, Chugh Ankita

机构信息

Department of Pathology, All India Institute of Medical Sciences, Rajasthan, India.

出版信息

Oman Med J. 2023 May 31;38(3):e511. doi: 10.5001/omj.2023.16. eCollection 2023 May.

DOI:10.5001/omj.2023.16
PMID:37313250
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10259156/
Abstract

COVID-19 is a relatively new disease whose complete pathogenesis and complications have not been elucidated. Apart from the morbidity and mortality caused by the virus itself, it is noted that patients affected with this virus have a higher susceptibility to bacterial and fungal co-infections. Mucormycosis is a rare and life-threatening fungal infection generally associated with uncontrolled diabetes mellitus and immunosuppression. It tends to rapid disease progression and poor prognosis if not diagnosed and managed promptly. There has been a sudden increase in the number of mucormycosis cases in patients with moderate to severe COVID-19 infection in the past few months. Herein, we present a series of 10 mucormycosis cases diagnosed over one week.

摘要

新型冠状病毒肺炎(COVID-19)是一种相对较新的疾病,其完整的发病机制和并发症尚未阐明。除了病毒本身引起的发病率和死亡率外,值得注意的是,感染这种病毒的患者更容易发生细菌和真菌合并感染。毛霉病是一种罕见且危及生命的真菌感染,通常与未控制的糖尿病和免疫抑制有关。如果不及时诊断和治疗,它往往会导致疾病迅速进展且预后不良。在过去几个月中,中度至重度COVID-19感染患者中毛霉病病例数突然增加。在此,我们报告了在一周内确诊的10例毛霉病病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcc/10259156/9f80fd654b09/OMJ-38-03-2100095-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcc/10259156/8d26df1b1ed9/OMJ-38-03-2100095-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcc/10259156/9f80fd654b09/OMJ-38-03-2100095-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcc/10259156/8d26df1b1ed9/OMJ-38-03-2100095-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcc/10259156/9f80fd654b09/OMJ-38-03-2100095-f2.jpg

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J Med Cases. 2021 Mar;12(3):85-89. doi: 10.14740/jmc3637. Epub 2021 Jan 19.
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Sino-orbital mucormycosis in a COVID-19 patient: A case report.一名新冠肺炎患者的鼻窦眼眶毛霉菌病:病例报告
Int J Surg Case Rep. 2021 May;82:105957. doi: 10.1016/j.ijscr.2021.105957. Epub 2021 May 4.
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Title of the Article: Paranasal Mucormycosis in COVID-19 Patient.文章标题:新冠病毒感染患者的鼻旁窦毛霉病
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SARS-CoV-2, Uncontrolled Diabetes and Corticosteroids-An Unholy Trinity in Invasive Fungal Infections of the Maxillofacial Region? A Retrospective, Multi-centric Analysis.严重急性呼吸综合征冠状病毒2型、未控制的糖尿病与皮质类固醇——颌面区域侵袭性真菌感染中的“邪恶三位一体”?一项回顾性多中心分析
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The double-edged sword of systemic corticosteroid therapy in viral pneumonia: A case report and comparative review of influenza-associated mucormycosis versus COVID-19 associated mucormycosis.系统性皮质类固醇治疗病毒性肺炎的双刃剑:一例流感相关性毛霉菌病与 COVID-19 相关性毛霉菌病的对比分析。
Mycoses. 2021 Aug;64(8):798-808. doi: 10.1111/myc.13256. Epub 2021 Mar 5.
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Mucor in a Viral Land: A Tale of Two Pathogens.霉菌在病毒之地:两种病原体的故事。
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