Tang Kai-Yuan, Sun Bi-Yun, Yan Yan, Wang Xi, He Xin, Liu Zhi-Shun
Department of Acupuncture and Moxibustion, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China; Department of TCM, Guiyang Fourth People's Hospital, Guiyang 550007, Guizhou Province.
Institute of Sports Medicine, General Administration of Sport of China.
Zhongguo Zhen Jiu. 2023 Jun 12;43(6):622-6. doi: 10.13703/j.0255-2930.20220530-k0004.
To compare the clinical efficacy of acupuncture with different frequencies in the treatment of patients with functional dyspepsia (FD).
A total of 90 patients with FD were randomly divided into a 3-time acupuncture treatment per week group (3-A group, 31 cases, 2 cases dropped off), a 1-time acupuncture treatment per week group (1-A group, 30 cases, 2 cases dropped off) and a control group (29 cases, 2 cases dropped off). In the two acupuncture groups, the acupoints were Zhongwan (CV 12) and bilateral Tianshu (ST 25), Neiguan (PC 6), Liangqiu (ST 34), Yanglingquan (GB 34), Zusanli (ST 36) and Taichong (LR 3), stimulated 3 times a week and once a week, respectively; and the treatment was given consecutively for 4 weeks. In the control group, no intervention was adopted, but the compensatory therapy was provided after the end of follow-up. The scores of the symptom index of dyspepsia (SID), self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were compared among the 3 groups before treatment, after 4 weeks of treatment and in 4 and 8 weeks after treatment completion separately. The score of Nepean dyspepsia life quality index (NDLQI) was evaluated before treatment, after 2 and 4 weeks of treatment and in 4 and 8 weeks after treatment completion.
After 4 weeks of treatment and in 4 and 8 weeks after treatment completion, the scores of SID, SAS and SDS were all reduced in the 3-A group and the 1-A group when compared with the scores before treatment (<0.000 1, <0.05). After 4 weeks of treatment, the scores of SID, SAS and SDS in the two acupuncture groups were lower than those in the control group (<0.000 1). After 2 and 4 weeks of treatment, the increased values of NDLQI score in the two acupuncture groups were all higher than those in the control group (<0.05). In 4 and 8 weeks after treatment completion, the scores of SID, SAS and SDS in the 3-A group were lower than those in the 1-A group (<0.001, <0.05), and the increased values of NDLQI score in the 3-A group were higher than those in the 1-A group (<0.000 1).
Acupuncture given 3 times per week is superior to the treatment given once per week in the aspects of relieving the clinical symptoms, improving the quality of life and regulating the emotional state in patients with FD. This efficacy is persistent for 8 weeks after treatment completion.
比较不同频率针刺治疗功能性消化不良（FD）患者的临床疗效。
将90例FD患者随机分为每周针刺3次组（3-A组，31例，脱落2例）、每周针刺1次组（1-A组，30例，脱落2例）和对照组（29例，脱落2例）。在两个针刺组中，穴位选取中脘（CV 12）、双侧天枢（ST 25）、内关（PC 6）、梁丘（ST 34）、阳陵泉（GB 34）、足三里（ST 36）和太冲（LR 3），分别每周针刺3次和1次；连续治疗4周。对照组不采取干预措施，但在随访结束后给予代偿性治疗。分别比较3组治疗前、治疗4周后、治疗结束后4周和8周时消化不良症状指数（SID）、自评焦虑量表（SAS）和自评抑郁量表（SDS）的评分。在治疗前、治疗2周和4周后、治疗结束后4周和8周时评估纽卡斯尔消化不良生活质量指数（NDLQI）评分。
治疗4周后及治疗结束后4周和8周时，3-A组和1-A组的SID、SAS和SDS评分与治疗前相比均降低（<0.000 1，<0.05）。治疗4周后，两个针刺组的SID、SAS和SDS评分均低于对照组（<0.000 1）。治疗2周和4周后，两个针刺组的NDLQI评分增加值均高于对照组（<0.05）。治疗结束后4周和8周时，3-A组的SID、SAS和SDS评分低于1-A组（<0.001，<0.05），3-A组的NDLQI评分增加值高于1-A组（<0.000 1）。
每周针刺3次在缓解FD患者临床症状、提高生活质量和调节情绪状态方面优于每周针刺1次。这种疗效在治疗结束后持续8周。
