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[微套管抽脂术在脂性水肿患者肿胀麻醉中的应用:519例抽脂术分析]

[Microcannular liposuction in tumescent anesthesia in lipedema patients: an analysis of 519 liposuctions].

作者信息

Kodim Alicia, Wollina Uwe

机构信息

Klinik für Dermatologie und Allergologie, Städtisches Klinikum Dresden, Akademisches Lehrkrankenhaus, Dresden, Deutschland, 01067.

出版信息

Wien Med Wochenschr. 2023 Sep;173(11-12):290-298. doi: 10.1007/s10354-023-01017-5. Epub 2023 Jun 14.

DOI:10.1007/s10354-023-01017-5
PMID:37314596
Abstract

This is a retrospective analysis of all lipedema patients treated by tumescent liposuction at our department in the years 2007-2021: We performed 519 liposuctions in 178 patients with a mean age of 45 ± 15.5 years. By the stage of lipedema the mean age increased significantly, what underlines the concept of lipedema as a chronic progressive disorder. Three-thirds of patients reported at least one comorbidity. The most common were arterial hypertension (32.58%), obesity (24.16%), and hypothyroidism (20.79%). We removed a mean lipoaspirate volume of 4905 ± 2800 mL. A major target for treatment is pain reduction. All patients reported at least a 50% pain reduction after liposuction, while 96 achieved a pain reduction ≥ 90%. The pre-operative pain intensity (p = 0.000) and the lipedema stage (p = 0.032) exerted a significant impact on absolute pain reduction. There was no association of pain reduction to volume loss. The post-operative rate of adverse events was 2.89%. Liposuction in tumescent anesthesia is an effective and safe method to reduce both pain and volume in patients with lipedema.

摘要

这是一项对2007年至2021年在我科室接受肿胀吸脂术治疗的所有脂肪性水肿患者的回顾性分析:我们对178例平均年龄为45±15.5岁的患者进行了519次吸脂手术。随着脂肪性水肿分期的增加,平均年龄显著上升,这突出了脂肪性水肿作为一种慢性进行性疾病的概念。三分之二的患者报告至少有一种合并症。最常见的是动脉高血压(32.58%)、肥胖症(24.16%)和甲状腺功能减退症(20.79%)。我们吸出的平均脂肪抽吸量为4905± 2800毫升。治疗的一个主要目标是减轻疼痛。所有患者在吸脂术后均报告疼痛至少减轻了50%,而96例患者疼痛减轻≥90%。术前疼痛强度(p = 0.000)和脂肪性水肿分期(p = 0.032)对绝对疼痛减轻有显著影响。疼痛减轻与体积减少无关。术后不良事件发生率为2.89%。肿胀麻醉下的吸脂术是一种有效且安全的方法,可减轻脂肪性水肿患者的疼痛和减少体积。

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[Complications and their management in the surgical treatment of lipohyperplasia dolorosa].[痛性脂肪过多症手术治疗中的并发症及其处理]
Dermatologie (Heidelb). 2023 Feb;74(2):114-120. doi: 10.1007/s00105-022-05073-7. Epub 2022 Nov 9.
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Pathophysiology of cellulite: Possible involvement of selective endotoxemia.脂肪团的病理生理学:选择性内毒素血症的可能参与。
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Indications of Peripheral Pain, Dermal Hypersensitivity, and Neurogenic Inflammation in Patients with Lipedema.
脂肪水肿患者的周围性疼痛、皮肤感觉过敏和神经性炎症的指征。
Int J Mol Sci. 2022 Sep 7;23(18):10313. doi: 10.3390/ijms231810313.
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Characteristics and Patient Reported Outcome Measures in Lipedema Patients-Establishing a Baseline for Treatment Evaluation in a High-Volume Center.脂肪性水肿患者的特征及患者报告结局指标——在一个高容量中心建立治疗评估基线
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Surg Obes Relat Dis. 2022 May;18(5):628-633. doi: 10.1016/j.soard.2021.12.027. Epub 2022 Jan 7.
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A 10-Year Retrospective before-and-after Study of Lipedema Surgery: Patient-Reported Lipedema-Associated Symptom Improvement after Multistage Liposuction.脂肪水肿症手术前后 10 年回顾性研究:多阶段吸脂术后患者报告的脂肪水肿相关症状改善。
Plast Reconstr Surg. 2022 Mar 1;149(3):529e-541e. doi: 10.1097/PRS.0000000000008880.
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Lipedema and the Potential Role of Estrogen in Excessive Adipose Tissue Accumulation.脂肪水肿与雌激素在过度脂肪组织堆积中的潜在作用。
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Survey Outcomes of Lipedema Reduction Surgery in the United States.美国脂肪性水肿减少手术的调查结果
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BMC Womens Health. 2021 Jan 15;21(1):27. doi: 10.1186/s12905-021-01174-y.
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Disease progression and comorbidities in lipedema patients: A 10-year retrospective analysis.脂肪水肿患者的疾病进展和合并症:一项 10 年回顾性分析。
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