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美国脂肪性水肿减少手术的调查结果

Survey Outcomes of Lipedema Reduction Surgery in the United States.

作者信息

Herbst Karen L, Hansen Emily A, Cobos Salinas Leopoldo M, Wright Thomas F, Larson Ethan E, Schwartz Jaime S

机构信息

Department of Medicine, University of Arizona, Tucson, Ariz.

TREAT Program, University of Arizona, Tucson, Ariz.

出版信息

Plast Reconstr Surg Glob Open. 2021 Apr 23;9(4):e3553. doi: 10.1097/GOX.0000000000003553. eCollection 2021 Apr.

Abstract

BACKGROUND

Lipedema is a loose connective tissue disease affecting the limbs of women, that is difficult to lose by diet, exercise, or bariatric surgery. Publications from Europe demonstrate that lipedema reduction surgery improves quality of life for women with lipedema. There are no comparable studies in the United States (USA). The aim of this study was to collect data from women with lipedema in the USA who have undergone lipedema reduction surgery in the USA to determine if quality of life, pain, and other measures improved after lipedema reduction surgery.

METHODS

Subjects were recruited and consented online for a 166-item questionnaire in REDCap. In total, 148 women answered the questionnaire after undergoing lipedema reduction surgery in the USA. Significance set at < 0.05 was determined by ANOVA, Tukey's multiple comparison test, or paired -test.

RESULTS

Quality of life improved in 84% and pain improved in 86% of patients. Ambulation improved most in lipedema Stage 3 (96%). Weight loss occurred in all stages by 3 months after surgery. Complications included growth of loose connective tissue within and outside treated areas, tissue fibrosis, anemia, blood clots, and lymphedema.

CONCLUSIONS

Women with lipedema noticed significant benefits after lipedema reduction surgery in the USA. Prospective studies are needed to assess benefits and complications after lipedema reduction surgery in the USA.

摘要

背景

脂肪性水肿是一种影响女性四肢的疏松结缔组织疾病,通过饮食、运动或减肥手术难以消除。欧洲的出版物表明,脂肪性水肿减少手术可改善脂肪性水肿女性的生活质量。美国没有类似的研究。本研究的目的是收集在美国接受脂肪性水肿减少手术的美国脂肪性水肿女性的数据,以确定脂肪性水肿减少手术后生活质量、疼痛和其他指标是否有所改善。

方法

通过在线方式招募受试者,并征得他们同意在REDCap中填写一份166项的问卷。共有148名女性在美国接受脂肪性水肿减少手术后回答了问卷。显著性设定为<0.05,通过方差分析、Tukey多重比较检验或配对检验确定。

结果

84%的患者生活质量得到改善,86%的患者疼痛得到改善。脂肪性水肿3期患者的行走能力改善最为明显(96%)。术后3个月内,所有阶段的患者体重均有所减轻。并发症包括治疗区域内外疏松结缔组织生长、组织纤维化、贫血、血栓和淋巴水肿。

结论

在美国,脂肪性水肿女性在接受脂肪性水肿减少手术后获得了显著益处。需要进行前瞻性研究来评估美国脂肪性水肿减少手术后的益处和并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29de/8078351/fd1886c506f7/gox-9-e3553-g001.jpg

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