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椎板切除术后椎间盘间隙感染。文献综述及三例报告

Postlaminectomy disc space infection. A review of the literature and a report of three cases.

作者信息

Fernand R, Lee C K

出版信息

Clin Orthop Relat Res. 1986 Aug(209):215-8.

PMID:3731599
Abstract

Postlaminectomy disc space infection is a relatively modern disease that is frequently mentioned, rarely encountered, sometimes not recognized, and unquestionably iatrogenic. A total of 125 cases have been reported since 1947. The bulk of the evidence favors a bacteriologic agent, but the route of infection is still not clear, because both hematogenous and local origins are possible in a surgically traumatized area with poor blood supply. This report of three additional cases emphasizes the variety of presentations. The diagnosis is difficult but can be made if it is suspected. Patients complain of recurrent pain after initial relief of symptoms. Muscle spasm, elevated temperature, and positive straight leg raising test are the most common signs. Increased sedimentation rate is almost always present. The roentgenographic findings appear several weeks after the initial symptoms. Radioisotope and CAT scans may be helpful earlier. Needle biopsy/aspiration under image intensification increases the frequency of bacteriologic identification. Conservative management based on bed rest, immobilization, and antibiotics remains the treatment of choice. Early surgical treatment may be indicated in some cases and seems to eradicate the disease, hastening recovery. Late surgical intervention, when indicated, is facilitated by an anterior approach.

摘要

椎板切除术后椎间盘间隙感染是一种相对现代的疾病,常被提及,但很少遇到,有时难以识别,且无疑是医源性的。自1947年以来共报告了125例。大量证据支持细菌病原体感染,但感染途径仍不明确,因为在血供较差的手术创伤区域,血源性和局部源性感染均有可能。本文报告另外3例病例,强调了其临床表现的多样性。诊断困难,但如果怀疑该病则可做出诊断。患者在最初症状缓解后又出现反复疼痛。肌肉痉挛、体温升高和直腿抬高试验阳性是最常见的体征。血沉几乎总是升高。X线表现出现在初始症状出现数周后。放射性同位素扫描和计算机断层扫描(CAT)可能在早期更有帮助。影像增强引导下的针吸活检可提高细菌鉴定的频率。以卧床休息、固定和使用抗生素为基础的保守治疗仍是首选治疗方法。在某些情况下可能需要早期手术治疗,手术似乎可以根除疾病,加速康复。若需要进行晚期手术干预,前路手术更方便。

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