Epstein F H
Cor Vasa. 1986;28(2):83-9.
Coronary heart disease presents in a disturbingly high percentage of instances as sudden death. A large percentage of cases occur outside the hospital, outside the reach of emergency care. Data on the frequency of sudden death, within the framework of coronary heart disease incidence, are presented. The risk factors for sudden death, as far as it is known, are similar in kind and predictive power to those for myocardial infarction with survival. While there is a great need for new tests which predict susceptibility to sudden death with adequate sensitivity and specificity, the lesson to be learned from all the knowledge already gained is that prevention of premature coronary heart disease as a whole, through appropriate changes in life style, will correspondingly reduce the risk of sudden death in the population as well. This knowledge must be put into action and should have an appreciable effect on the frequency of sudden death while more research on the mechanisms of the condition is being conducted.
冠心病在相当高比例的病例中表现为猝死。很大一部分病例发生在医院外,无法获得急诊护理。本文呈现了在冠心病发病率框架内猝死频率的数据。就目前所知,猝死的危险因素在种类和预测能力上与伴有生存的心肌梗死的危险因素相似。虽然迫切需要能够以足够的敏感性和特异性预测猝死易感性的新检测方法,但从已获得的所有知识中吸取的教训是,通过适当改变生活方式来整体预防早发性冠心病,也将相应降低人群中猝死的风险。这一知识必须付诸行动,并且在对该疾病机制进行更多研究的同时,应对猝死频率产生显著影响。