Wen J
Zhonghua Zhong Liu Za Zhi. 1986 Jan;8(1):70-2.
Endodermal sinus tumor can be found in the ovaries, testes and extragonadal sites, such as sacrococcygeal, retroperitoneal, mediastinal regions or other mid line structures. Sacrococcygeal endodermal sinus tumor and its characteristics are presented. The age of patients with lesions in this region is youngest among all. Their ages ranged 10 months to 3 years in our series. Five of them were females. Most cases had difficulty in passing stools. When first seen in the clinic, all were in the advanced stage with the tumor infiltrating into the sacrococcygeal bones, presacral soft tissues and rectum already. The residual lesions recurred rapidly after operation. All cases were not treated systematically by chemotherapy or radiotherapy, and died within 1-15 months. Pathologically, the composition of the tumor is the same in every site, assuming patterns of reticular or solid, glandular or pseudopapillary appearance, Schillar-Duval bodies, hyaline bodies and so on. Positive serum AFP test may be helpful in the differential diagnosis and prognostic evaluation.
内胚窦瘤可发生于卵巢、睾丸及性腺外部位，如骶尾部、腹膜后、纵隔区域或其他中线结构。本文介绍了骶尾部内胚窦瘤及其特点。该区域病变患者的年龄在所有患者中最小。在我们的系列研究中，患者年龄为10个月至3岁。其中5例为女性。大多数病例存在排便困难。初诊时，所有病例均处于晚期，肿瘤已浸润至骶尾骨、骶前软组织和直肠。术后残留病灶复发迅速。所有病例均未接受系统的化疗或放疗，在1至15个月内死亡。病理上，肿瘤在各个部位的组成相同，呈现网状或实性、腺管状或假乳头状外观、席勒-杜瓦尔小体、透明小体等形态。血清甲胎蛋白检测呈阳性可能有助于鉴别诊断和预后评估。
