Zillessen E, Palme W, Feichter G E
Dtsch Med Wochenschr. 1986 Aug 1;111(31-32):1200-7. doi: 10.1055/s-2008-1068607.
Clinical findings, symptoms and predisposing factors were studied in 43 patients with oesophageal candidiasis, 40 patients with peptic oesophagitis and 40 normal controls. Oesophageal candidiasis was confirmed cytologically. 2.4% of patients who had undergone gastroscopy had oesophageal candidiasis; only three of them had simultaneous candidiasis of the oral cavity. Cardiac failure, oesophageal varices, hiatus hernia and gastric ulcer were common associated disorders. 42% of patients with candidal oesophagitis were symptom-free. Most common symptoms were vomiting, retrosternal and epigastric pain. Peptic oesophagitis was more frequently associated with symptoms. Predisposing factors were present in 88% of cases of oesophageal candidiasis: alcoholism, hepatic cirrhosis, diabetes mellitus, malignant tumours and other wasting diseases. 18 patients had had treatment with cimetidine; they included all 13 patients whose candidiasis was first detected at check endoscopy.
对43例食管念珠菌病患者、40例消化性食管炎患者和40例正常对照者的临床检查结果、症状及诱发因素进行了研究。食管念珠菌病经细胞学检查确诊。接受胃镜检查的患者中2.4%患有食管念珠菌病;其中只有3例同时患有口腔念珠菌病。心力衰竭、食管静脉曲张、食管裂孔疝和胃溃疡是常见的相关疾病。42%的念珠菌性食管炎患者无症状。最常见的症状是呕吐、胸骨后疼痛和上腹部疼痛。消化性食管炎与症状的关联更为频繁。88%的食管念珠菌病病例存在诱发因素:酗酒、肝硬化、糖尿病、恶性肿瘤和其他消耗性疾病。18例患者曾接受西咪替丁治疗;其中包括在内镜检查时首次发现念珠菌病的所有13例患者。