Koller E A, Studer R, Gerber H, Stüssi E
Eur J Appl Physiol Occup Physiol. 1986;55(3):307-14. doi: 10.1007/BF02343804.
Whole-body microvibrations (MV) in three dimensions were measured in 51 volunteers, all medical students, 26 without and 25 with beta-receptor blockade (propranolol), immediately before a practical physiology examination and during the ensuing vacation. Propranolol impeded the increase in MV values in all three axes, significantly those in the z axis (vertical), the differences in MV values between the two measurements being minimal in the beta-receptor blocked group. On the other hand, propranolol enhanced MV in the x axis (anteroposterior) and the y axis (transverse), the y axis difference being significant only in females. Propranolol obviously relieves examination stress: the majority of candidates (52%) felt "quieter" in the examination with than in other similar situations without beta-receptor blockade. Propranolol was, however, without effect on the examination results. The rectified impulse in the z axis when related to body weight (Jz) correlates linearly with the calculated cardiac output. Propranolol, however, reduced cardiac output more than Jz, pointing to a Jz component non-sensitive to beta-receptor blockade. The part played by muscle tonus, mainly reflected in the y axis, thus remains unknown. The large and slow oscillations in the x and y axes, observed particularly in beta-receptor blocked females, might be attributed to diminution in standing ability.
对51名志愿者（均为医科学生）进行了全身三维微振动（MV）测量，其中26人未服用β受体阻滞剂，25人服用了β受体阻滞剂（普萘洛尔），分别在一次生理学实践考试前及随后的假期期间进行测量。普萘洛尔抑制了三个轴向上MV值的增加，在z轴（垂直方向）上的抑制作用尤为显著，在β受体阻滞剂组中，两次测量之间MV值的差异最小。另一方面，普萘洛尔增加了x轴（前后方向）和y轴（横向）上的MV，仅在女性中y轴差异显著。普萘洛尔明显缓解了考试压力：大多数考生（52%）感觉考试时比未服用β受体阻滞剂的其他类似情况下“更平静”。然而，普萘洛尔对考试成绩没有影响。z轴上与体重相关的整流脉冲（Jz）与计算出的心输出量呈线性相关。然而，普萘洛尔降低心输出量的幅度大于Jz，这表明存在一个对β受体阻滞剂不敏感的Jz成分。主要反映在y轴上的肌肉紧张度所起的作用仍然未知。在x轴和y轴上观察到的大而缓慢的振荡，特别是在服用β受体阻滞剂的女性中，可能归因于站立能力的下降。
