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Pharmacokinetics of propranolol in normal healthy volunteers.

作者信息

Gomeni R, Bianchetti G, Sega R, Morselli P L

出版信息

J Pharmacokinet Biopharm. 1977 Jun;5(3):183-92. doi: 10.1007/BF01065394.

DOI:10.1007/BF01065394
PMID:881640
Abstract
摘要

相似文献

1
Pharmacokinetics of propranolol in normal healthy volunteers.普萘洛尔在正常健康志愿者体内的药代动力学。
J Pharmacokinet Biopharm. 1977 Jun;5(3):183-92. doi: 10.1007/BF01065394.
2
Analysis and disposition of low dose oral propranolol.低剂量口服普萘洛尔的分析与处置
Res Commun Chem Pathol Pharmacol. 1978 Jun;20(3):531-8.
3
Pharmacokinetic study of a new sustained release preparation of propranolol in normal healthy volunteers.
Int J Clin Pharmacol Ther Toxicol. 1988 Sep;26(9):436-8.
4
Potential drug interactions with misoprostol: effects on the pharmacokinetics of antipyrine and propranolol.米索前列醇的潜在药物相互作用：对安替比林和普萘洛尔药代动力学的影响。
Postgrad Med J. 1988;64 Suppl 1:21-4.
5
Increased clearance of propranolol in thyrotoxicosis.甲状腺毒症时普萘洛尔清除率增加。
Ann Intern Med. 1981 Apr;94(4 pt 1):472-4. doi: 10.7326/0003-4819-94-4-472.
6
Effect of exercise on propranolol pharmacokinetics.运动对普萘洛尔药代动力学的影响。
Eur J Clin Pharmacol. 1990;39(4):391-4. doi: 10.1007/BF00315416.
7
Pharmacodynamics and pharmacokinetics of single doses of ketanserin and propranolol alone and in combination in healthy volunteers.单剂量酮色林和普萘洛尔单独及联合应用于健康志愿者的药效学和药代动力学。
Br J Clin Pharmacol. 1986 Sep;22(3):301-8. doi: 10.1111/j.1365-2125.1986.tb02891.x.
8
Effect of diltiazem on the pharmacokinetics of propranolol, metoprolol and atenolol.地尔硫䓬对普萘洛尔、美托洛尔和阿替洛尔药代动力学的影响。
Eur J Clin Pharmacol. 1989;36(1):67-70. doi: 10.1007/BF00561026.
9
Pharmacokinetics of dextro-, laevo- and racemic propranolol in man.
Eur J Clin Pharmacol. 1972 Mar;4(2):74-6. doi: 10.1007/BF00562500.
10
Relationship of propranolol pharmacokinetics to antihypertensive effect and beta-adrenergic blockade in the treatment of hypertension.普萘洛尔药代动力学与高血压治疗中降压效果及β-肾上腺素能阻滞的关系。
Eur J Clin Pharmacol. 1980 Nov;18(5):391-4. doi: 10.1007/BF00636790.

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Clinical pharmacokinetics of buffered propranolol sublingual tablet (Promptol™)-application of a new "physiologically based" model to assess absorption and disposition.缓冲型普萘洛尔舌下片剂（Promptol™）的临床药代动力学-应用新型“生理基础”模型评估吸收和处置。
AAPS J. 2013 Jul;15(3):787-96. doi: 10.1208/s12248-013-9479-1. Epub 2013 Apr 19.
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Ontogeny of drug elimination by the human kidney.人肾脏药物消除的个体发生学。
Pediatr Nephrol. 2006 Feb;21(2):160-8. doi: 10.1007/s00467-005-2105-4. Epub 2005 Dec 6.
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Pharmacokinetics of propranolol.

本文引用的文献

1
Concept of a volume of distribution and possible errors in evaluation of this parameter.分布容积的概念以及该参数评估中可能存在的误差。
J Pharm Sci. 1968 Jan;57(1):128-33. doi: 10.1002/jps.2600570125.
2
Assessment of pharmacokinetic constants from postinfusion blood curves obtained after I.V. infusion.通过静脉输注后获得的输注后血药浓度曲线评估药代动力学常数。
J Pharm Sci. 1970 Jan;59(1):53-5. doi: 10.1002/jps.2600590107.
3
The disposition of propranolol. I. Elimination during oral absorption in man.普萘洛尔的处置。I. 人体口服吸收过程中的消除
普萘洛尔的药代动力学
J Pharmacokinet Biopharm. 1981 Aug;9(4):419-29. doi: 10.1007/BF01060886.
4
Pharmacokinetics of lidocaine and its deethylated metabolite: dose and time dependency studies in man.利多卡因及其脱乙基代谢物的药代动力学：人体剂量和时间依赖性研究
J Pharmacokinet Biopharm. 1982 Jun;10(3):265-81. doi: 10.1007/BF01059261.
5
Variable first-pass elimination of propranolol following single and multiple oral doses in hypertensive patients.高血压患者单次及多次口服普萘洛尔后的首过消除率可变。
Eur J Drug Metab Pharmacokinet. 1982;7(3):183-9. doi: 10.1007/BF03189564.
6
Kinetics and cardiac effects of propranolol in humans.普萘洛尔在人体中的动力学及心脏效应
Klin Wochenschr. 1982 May 17;60(10):521-5. doi: 10.1007/BF01756098.
7
Prediction of bioavailability for drugs with a high first-pass effect using oral clearance data.利用口服清除率数据预测具有高首过效应药物的生物利用度。
Eur J Clin Pharmacol. 1982;22(1):85-90. doi: 10.1007/BF00606430.
8
Dose-dependent pharmacokinetics and cancer chemotherapy.剂量依赖性药代动力学与癌症化疗
Cancer Chemother Pharmacol. 1981;6(1):1-9. doi: 10.1007/BF00253003.
9
A standard approach to compiling clinical pharmacokinetic data.一种汇编临床药代动力学数据的标准方法。
J Pharmacokinet Biopharm. 1981 Feb;9(1):59-127. doi: 10.1007/BF01059343.
10
Stable oral availability of sustained release propranolol when co-administered with hydralazine or food: evidence implicating substrate delivery rate as a determinant of presystemic drug interactions.与肼屈嗪或食物合用时，缓释普萘洛尔的口服稳定性：有证据表明底物递送速率是系统性前药物相互作用的一个决定因素。
Br J Clin Pharmacol. 1984;17 Suppl 1(Suppl 1):45S-50S. doi: 10.1111/j.1365-2125.1984.tb02427.x.
Pharmacology. 1972;7(3):159-68. doi: 10.1159/000136285.
4
Normalization in the fitting of data by iterative methods. Application to tracer kinetics and enzyme kinetics.迭代法拟合数据中的归一化。在示踪动力学和酶动力学中的应用。
Biochem J. 1973 Jul;134(3):729-36. doi: 10.1042/bj1340729.
5
A sensitive gas chromatographic method for the determination of propranolol in human plasma.一种用于测定人血浆中普萘洛尔的灵敏气相色谱法。
J Chromatogr. 1973 Sep 26;84(2):347-53. doi: 10.1016/s0021-9673(01)91714-5.
6
Disposition of propranolol. VI. Independent variation in steady-state circulating drug concentrations and half-life as a result of plasma drug binding in man.普萘洛尔的处置。VI. 人体中血浆药物结合导致稳态循环药物浓度和半衰期的独立变化。
Clin Pharmacol Ther. 1973 Jul-Aug;14(4):494-500. doi: 10.1002/cpt1973144part1494.
7
Statistical estimations in pharmacokinetics.药物动力学中的统计学估计
J Pharmacokinet Biopharm. 1974 Apr;2(2):123-48. doi: 10.1007/BF01061504.
8
Pharmacokinetics of oral propranolol in chronic renal disease.慢性肾病患者口服普萘洛尔的药代动力学
Clin Pharmacol Ther. 1974 Nov;16(5 Part 1):761-9. doi: 10.1002/cpt1974165part1761.
9
The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat.普萘洛尔的处置。3. 由于人、猴、狗和大鼠体内的血浆结合作用，半衰期和分布容积降低。
J Pharmacol Exp Ther. 1973 Jul;186(1):114-22.
10
Contribution of the liver to overall elimination of propranolol.
J Pharmacokinet Biopharm. 1976 Feb;4(1):17-27. doi: 10.1007/BF01271441.