Postgraduate Studies Program in Food, Nutrition and Health, Department of Nutrition, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Facultad de Medicina, Universidad del Azuay, Cuenca, Ecuador.
Br J Nutr. 2023 Dec 28;130(12):2162-2173. doi: 10.1017/S0007114523001356. Epub 2023 Jun 16.
The association between dairy products consumption in adults and the likelihood of type 2 diabetes mellitus (T2DM) has been described, but more information on the adolescent population is needed. This nationally representative, cross-sectional school-based study aimed to describe the consumption of dairy products and their subtypes and to evaluate their association with prediabetes and T2DM in adolescents. The Study of Cardiovascular Risks in Adolescents (ERICA) includes adolescents aged 12-17 years. Dairy products consumption was evaluated by 24-h food recall. Associations with fasting glucose, glycated hemoglobin (HbA1c) and insulin resistance, as measured by homeostatic model assessment-insulin resistance (HOMA-IR), were evaluated by multivariate linear regression. Poisson regression was also used to assess the association between dairy products consumption and the combined prevalence of prediabetes and T2DM. Models were adjusted for sociodemographic, nutritional, behavioural and anthropometrics. The final sample analysed consisted of 35 614 adolescents. Total intake of dairy products was inversely associated with fasting blood glucose levels after adjusting for all covariates ( = -0·452, 95 % CI -0·899, -0·005). The associations were stronger for overweight and obese adolescents. Findings were similar for full-fat dairy products and yogurt. Higher consumption of low-fat dairy products and cheese were associated with a 46 % (prevalence ratio, PR 1·46, 95 % CI 1·18, 1·80) and 33 % (PR 1·33, 95 % CI 1·14, 1·57) higher combined prevalence of prediabetes and T2DM, respectively. The total consumption of dairy products and full-fat dairy products was associated with a lower combined prevalence of prediabetes and T2DM, while the consumption of cheese and low-fat dairy products was associated with higher combined prevalence of prediabetes and T2DM in Brazilian adolescents.
乳制品消费与成年人 2 型糖尿病(T2DM)的关系已被描述,但青少年人群的数据仍需更多信息。本研究是一项全国代表性的、基于学校的横断面研究,旨在描述青少年乳制品的消费情况及其亚类,并评估其与青少年前驱糖尿病和 T2DM 的关系。青少年心血管风险研究(ERICA)纳入了 12-17 岁的青少年。通过 24 小时食物回忆评估乳制品的消费情况。采用多元线性回归评估空腹血糖、糖化血红蛋白(HbA1c)和胰岛素抵抗(通过稳态模型评估-胰岛素抵抗[HOMA-IR]评估)与乳制品消费的相关性。还使用泊松回归评估乳制品消费与前驱糖尿病和 T2DM 联合患病率之间的相关性。模型调整了社会人口统计学、营养、行为和人体测量学因素。最终分析样本包括 35614 名青少年。在调整所有协变量后,乳制品总摄入量与空腹血糖水平呈负相关(=-0.452,95%CI-0.899,-0.005)。对于超重和肥胖青少年,相关性更强。全脂乳制品和酸奶的结果相似。较高的低脂乳制品和奶酪摄入量与前驱糖尿病和 T2DM 联合患病率分别增加 46%(患病率比[PR]1.46,95%CI1.18,1.80)和 33%(PR1.33,95%CI1.14,1.57)。乳制品和全脂乳制品的总摄入量与前驱糖尿病和 T2DM 的联合患病率降低有关,而奶酪和低脂乳制品的摄入量与前驱糖尿病和 T2DM 的联合患病率升高有关。