Pavía J, García A, Abelló R, Franch M, de España R, Herranz R
Eur J Nucl Med. 1986;11(12):470-3. doi: 10.1007/BF00252791.
A study has been carried out to assess the mucociliary function of nasal mucosa in 30 patients: 16 had undergone surgery due to larynx malignancy and the remaining 14 were divided in two groups. The first group was composed of seven patients suffering from larynx cancer but not operated, and the second group of seven had pathology not related to the airways (control group). The method used a 99mtechnetium sulphur colloid drop deposited on the nasal mucosa of one nostril. To calculate the rate of transport, a new method of quantification has been introduced, based on the formation of a parametric image. The mean velocity in laryngectomees was 3.6 mm/min (range 1.1-6.4). It was compared with the group of 14 patients without tracheostomy (mean 5.3, range 3.3-8.2). An impaired Student's-t-test gave a significant difference between both groups (P less than 0.005). The comparison between patients with nonoperated larynx cancer and normals gave a nonsignificant difference. The 16 operated patients were arbitrarily divided into two groups as per the time elapsed from laryngectomy; seven were studied within the first 3 years of operation and seven other patients after this term. The comparison between them was not significant.
一项研究对30例患者的鼻黏膜黏液纤毛功能进行了评估：16例因喉癌接受了手术，其余14例分为两组。第一组由7例未接受手术的喉癌患者组成，第二组7例患者的病理情况与气道无关（对照组）。该方法是将99m锝硫胶体滴置于一侧鼻孔的鼻黏膜上。为了计算传输速率，引入了一种基于参数图像形成的新量化方法。喉切除患者的平均速度为3.6毫米/分钟（范围为1.1 - 6.4）。将其与14例未行气管造口术的患者组（平均5.3，范围3.3 - 8.2）进行比较。采用非配对t检验，两组之间存在显著差异（P小于0.005）。未接受手术的喉癌患者与正常患者之间的比较无显著差异。16例接受手术的患者根据喉切除术后经过的时间被任意分为两组；7例在手术后的前3年内进行研究，另外7例在该时间段之后进行研究。两组之间的比较无显著差异。
