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年龄、性别和种族对鼻黏膜纤毛清除功能的影响。

Influence of age, gender, and ethnicity on nasal mucociliary clearance function.

作者信息

Kao C H, Jiang R S, Wang S J, Yeh S H

机构信息

Department of Nuclear Medicine, Taiwan, Republic of China.

出版信息

Clin Nucl Med. 1994 Sep;19(9):813-6. doi: 10.1097/00003072-199409000-00015.

DOI:10.1097/00003072-199409000-00015
PMID:7982319
Abstract

Nasal mucociliary clearance functions were measured in 46 healthy Chinese adult subjects (21 women and 25 men; age range, 27 to 75 years). A single droplet of Tc-99m MAA was placed on the floor of the nasal meatus about 1 cm behind the mucocutaneous junction, and its course was followed with a gamma camera. The nasal mucociliary clearance function was presented as the velocity (mm/minute) of nasal mucociliary transport of the Tc-99m MAA droplet. The results showed the velocity to be 4.42 +/- 2.12 mm/minute (4.61 +/- 2.37 mm/minute in the right nostril; 4.24 +/- 1.83 mm/minute in the left nostril). When the patients were grouped according to age or gender the velocity was 4.8 +/- 1.9 mm/minute (right nostril), 4.4 +/- 1.9 mm/minute (left nostril) in the older subjects (60 years and older), and 4.4 +/- 2.7 mm/minute (right nostril), 4.1 +/- 1.8 mm/minute (left nostril). In the younger subjects (59 years old and younger) (P > 0.05) the velocity was 5.0 +/- 2.7 mm/minute (right nostril), 4.3 +/- 1.8 mm/minute (left nostril) in men and 4.1 +/- 2.0 mm/minute (right nostril), 4.2 +/- 2.0 mm/minute (left nostril), in women (P > 0.05). The authors concluded that the influence of age or gender on healthy Chinese adults is not apparent. In addition, the velocity of flow in Chinese adults is slower than those in other previously reported ethnic studies.

摘要

对46名中国健康成年受试者(21名女性和25名男性;年龄范围为27至75岁)的鼻黏液纤毛清除功能进行了测量。将一滴99m锝标记的巨聚白蛋白(Tc-99m MAA)置于鼻道底部黏膜皮肤交界处后方约1厘米处,并用γ相机跟踪其移动过程。鼻黏液纤毛清除功能以99m锝标记的巨聚白蛋白液滴的鼻黏液纤毛运输速度(毫米/分钟)表示。结果显示速度为4.42±2.12毫米/分钟(右鼻孔为4.61±2.37毫米/分钟;左鼻孔为4.24±1.83毫米/分钟)。当根据年龄或性别对患者进行分组时,老年受试者(60岁及以上)的速度为4.8±1.9毫米/分钟(右鼻孔),4.4±1.9毫米/分钟(左鼻孔),年轻受试者(59岁及以下)中,男性速度为5.0±2.7毫米/分钟(右鼻孔),4.3±1.8毫米/分钟(左鼻孔),女性速度为4.1±2.0毫米/分钟(右鼻孔),4.2±2.0毫米/分钟(左鼻孔)(P>0.05)。作者得出结论,年龄或性别对中国健康成年人的影响不明显。此外,中国成年人的流动速度比其他先前报道的种族研究中的速度要慢。

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