Khan Jahanzeb, Bibi Saiqa, Naseem Irsa, Ahmed Shakeel, Hafeez Muhammad, Ahmed Khalil, Altaf Faizah, Dastan Davoud, Syed Asad, Jabir Majid S, Mohammed Mustafa K A, Tao Lin
Department of Chemistry, Mirpur University of Science and Technology (MUST), Mirpur, Azad Kashmir 10250, Pakistan.
Department of Chemistry, University of Azad Jammu & Kashmir, Muzaffarabad, Azad Kashmir 13100, Pakistan.
ACS Omega. 2023 Jun 2;8(23):21032-21041. doi: 10.1021/acsomega.3c01896. eCollection 2023 Jun 13.
In this work, we report the engineering of sub-30 nm nanocomposites of CuO/ZnO/NiO by using leaf extract. Zinc sulfate, nickel chloride, and copper sulfate were used as salt precursors, and isopropyl alcohol and water were used as solvents. The growth of nanocomposites was investigated by varying the concentrations of precursors and surfactants at pH 12. The as-prepared composites were characterized by XRD analysis and found to have CuO (monoclinic), ZnO (hexagonal primitive), and NiO (cubic) phases with an average size of 29 nm. FTIR analysis was performed to investigate the mode of fundamental bonding vibrations of the as-prepared nanocomposites. The vibrations of the prepared CuO/ZnO/NiO nanocomposite were detected at 760 and 628 cm, respectively. The optical bandgap energy of the CuO/NiO/ZnO nanocomposite was 3.08 eV. Ultraviolet-visible spectroscopy was performed to calculate the band gap by the Tauc approach. Antimicrobial and antioxidant activities of the synthesized CuO/NiO/ZnO nanocomposite were investigated. It was found that the antimicrobial activity of the synthesized nanocomposite increases with an increase in the concentration. The antioxidant activity of the synthesized nanocomposite was examined by using both ABTS and DPPH assays. The obtained results show an IC value of 0.110 for the synthesized nanocomposite compared to DPPH and ABTS (0.512), which is smaller than that of ascorbic acid (IC = 1.047). Such a low IC value ensures that the antioxidant potential of the nanocomposite is higher than that of ascorbic acid, which in turn shows their excellent antioxidant activity against both DPPH and ABTS.
在本研究中，我们报道了利用植物叶提取物制备出粒径小于30 nm的CuO/ZnO/NiO纳米复合材料。使用硫酸锌、氯化镍和硫酸铜作为盐前驱体，异丙醇和水作为溶剂。通过改变前驱体和表面活性剂在pH值为12时的浓度来研究纳米复合材料的生长情况。通过X射线衍射（XRD）分析对制备的复合材料进行表征，发现其具有CuO（单斜晶系）、ZnO（六方原始晶系）和NiO（立方晶系）相，平均粒径为29 nm。进行傅里叶变换红外光谱（FTIR）分析以研究制备的纳米复合材料的基本键合振动模式。制备的CuO/ZnO/NiO纳米复合材料的振动分别在760 cm和628 cm处被检测到。通过紫外可见光谱采用Tauc方法计算CuO/NiO/ZnO纳米复合材料的光学带隙能量为3.08 eV。对合成的CuO/NiO/ZnO纳米复合材料的抗菌和抗氧化活性进行了研究。发现合成的纳米复合材料的抗菌活性随浓度增加而增强。通过ABTS和DPPH两种测定方法检测了合成纳米复合材料的抗氧化活性。获得的结果表明，与DPPH和ABTS（IC = 0.512）相比，合成纳米复合材料的IC值为0.110，该值小于抗坏血酸的IC值（IC = 1.047）。如此低的IC值确保了纳米复合材料的抗氧化潜力高于抗坏血酸，这反过来表明它们对DPPH和ABTS均具有优异的抗氧化活性。
