Lahri Brajesh, Hussain Zakir, Gupta Neerja, Gupta Shikha, Singh Abhishek, Gupta Viney
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Department of Paediatrics, Genetics Division, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Am J Ophthalmol Case Rep. 2023 Jun 3;31:101867. doi: 10.1016/j.ajoc.2023.101867. eCollection 2023 Sep.
To report a case of diffuse xanthogranuloma presenting as bilateral anterior uveitis in a neonate.
A neonate was brought by the parents with complaints of redness, watering, and photophobia in both eyes for 10 days. Examination under anesthesia revealed the presence of bilateral hyphema, fibrinous membrane, corneal haze, and raised intraocular pressure (IOP). Ultrasound Biomicroscopy revealed diffuse bilateral iris thickening. The child was managed medically with topical glaucoma medications, topical steroids, and cycloplegics. The child responded well with the resolution of hyphema, anterior chamber inflammation, and reduction of IOP.
In neonates and infants presenting with bilateral uveitis, spontaneous hyphema, and secondary glaucoma, even in the absence of a well-defined iris lesion, diffuse juvenile xanthogranuloma should be considered as a differential diagnosis.
报告1例表现为双侧前葡萄膜炎的新生儿弥漫性黄色瘤。
患儿父母带一名新生儿前来就诊，患儿双眼发红、流泪及畏光10天。麻醉下检查发现双侧前房积血、纤维蛋白膜、角膜混浊及眼压升高。超声生物显微镜检查显示双侧虹膜弥漫性增厚。患儿接受了局部青光眼药物、局部类固醇和睫状肌麻痹剂的药物治疗。患儿前房积血、前房炎症消退，眼压降低，反应良好。
对于出现双侧葡萄膜炎、自发性前房积血和继发性青光眼的新生儿和婴儿，即使没有明确的虹膜病变，也应考虑弥漫性幼年黄色瘤作为鉴别诊断。
