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一例由科茨病导致的前房胆固醇沉着症及病例报告综述

A Case of Anterior Chamber Cholesterolosis Due to Coats' Disease and a Review of Reported Cases.

作者信息

Stacey Andrew W, Borri Melissa, Francesco Sonia De, Antenore Angela S, Menicacci Felice, Hadjistilianou Theodora

机构信息

Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, USA.

Unit of Ophthalmology, University of Siena, Policlinico "Santa Maria alle Scotte" Siena, Italy.

出版信息

Open Ophthalmol J. 2016 Feb 29;10:27-32. doi: 10.2174/1874364101610010027. eCollection 2016.

Abstract

PURPOSE

To present the case of an 18 month old boy with Coats' disease who was found to have anterior chamber cholesterolosis.

METHODS

Case presentation and review of reported cases.

RESULTS

An 18 month old boy presented with unilateral stage 3B Coats' disease without other clinical findings. Two weeks after presentation he returned with xanthocoria due to anterior chamber cholesterolosis. He subsequently developed hyphema, neovascular glaucoma, and was enucleated. His case is compared to all previously reported cases of Coats' disease leading to anterior chamber cholesterolosis.

CONCLUSION

The presentation of anterior chamber cholesterolosis in Coats' disease can range from the incidental finding in an asymptomatic patient to acute angle closure glaucoma with pain and acutely decreased vision. Clinicians should be aware of this potential complication of Coats' disease as it denotes a poor visual prognosis.

摘要

目的

报告一例18个月大患有科茨病的男孩,该患儿被发现有前房胆固醇沉着症。

方法

病例报告及对已报道病例的回顾。

结果

一名18个月大的男孩表现为单侧3B期科茨病,无其他临床症状。就诊两周后,因前房胆固醇沉着症出现黄瞳孔而复诊。随后他出现了前房积血、新生血管性青光眼,并最终接受了眼球摘除术。将他的病例与之前所有报道的导致前房胆固醇沉着症的科茨病病例进行了比较。

结论

科茨病中前房胆固醇沉着症的表现范围从无症状患者的偶然发现到伴有疼痛和视力急剧下降的急性闭角型青光眼。临床医生应意识到科茨病的这种潜在并发症,因为它预示着视力预后不良。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbf7/4780468/59e2c4f442eb/TOOPHTJ-10-27_F1.jpg

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