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感染委内瑞拉马脑炎病毒的小鼠纹状体中的游离氨基酸

Free amino acids in the striatum of mice infected with Venezuelan equine encephalomyelitis virus.

作者信息

Bonilla E, Prasad A L, Estévez J, Hernández H, Arrieta A

出版信息

Exp Neurol. 1986 Aug;93(2):434-9. doi: 10.1016/0014-4886(86)90205-0.

Abstract

In mice inoculated with the Guajira strain of Venezuelan equine encephalomyelitis virus, a significant increase in the concentration of arginine, isoleucine, leucine, glycine, phenylalanine, serine, threonine, and valine was produced in the striatum. On the contrary, the levels of alanine, asparagine, aspartate, GABA, glutamine, and taurine were reduced. No changes were observed in the striatal content of tyrosine and glutamic acid.

摘要

在接种委内瑞拉马脑炎病毒瓜希拉毒株的小鼠中,纹状体内精氨酸、异亮氨酸、亮氨酸、甘氨酸、苯丙氨酸、丝氨酸、苏氨酸和缬氨酸的浓度显著升高。相反,丙氨酸、天冬酰胺、天冬氨酸、γ-氨基丁酸、谷氨酰胺和牛磺酸的水平降低。酪氨酸和谷氨酸的纹状体含量未观察到变化。

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