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穿透性或钝性创伤患者的肾血管创伤及院内肾脏并发症

Traumatic injuries to the renal blood vessels and in-hospital renal complications in patients with penetrating or blunt trauma.

作者信息

Alzerwi Nasser A N

机构信息

Department of Surgery, College of Medicine, Majmaah University, Ministry of Education, Al-Majmaah City, Riyadh Region, Saudi Arabia.

出版信息

Front Surg. 2023 May 31;10:1134945. doi: 10.3389/fsurg.2023.1134945. eCollection 2023.

Abstract

BACKGROUND

Traumatic injuries to renal blood vessels (IRBV) can have significant consequences for patients, impacting their mortality, morbidity, and quality of life.

OBJECTIVE

This study aimed to compare trauma types and injury characteristics, vital signs, and outcomes in patients with and without IRBV (nIRBV) and examine whether IRBV and pre-existing renal dysfunction affected the likelihood of in-hospital renal complications (iHRC).

MATERIALS AND METHODS

After identifying penetrating and blunt trauma victims with IRBV in the National Trauma Data Bank, patient demographics, injury-related variables, treatment outcomes, and deaths under care were analyzed and compared.

RESULTS

Of the 994,184 trauma victims, 610 (0.6%) experienced IRBV. Victims in the IRBV group (IRBVG) had a significantly higher frequency of penetrating injuries (19.5% vs. 9.2%,  < 0.001) and higher injury severity score (ISS ≥25, 61.5% vs. 6.7%). Most injuries in both groups were unintentional, although a higher frequency of assault was noted in the IRBVG. The incidence of iHRC was higher in the IRBVG (6.6%) than in the nIRBVG (0.4%;  < 0.001). The IRBV {OR = 3.5 [95% CI = (2.4-5.0)]}, preexisting renal disorders {OR = 2.5 [95% CI = (2.1-2.9)]}, and in-hospital cardiac arrest {OR = 8.6 [95% CI = (7.7-9.5)]} were found to be among the factors associated with a higher risk of iHRC.

CONCLUSIONS

IRBV and pre-existing renal disorders considerably increased the risk of developing iHRC. Due to the long- and short-term consequences of associated cardiovascular, renal, and hemodynamic complications, victims of IRBV require specialized renal management and close monitoring.

摘要

背景

肾血管创伤性损伤(IRBV)会给患者带来严重后果,影响其死亡率、发病率和生活质量。

目的

本研究旨在比较有和没有IRBV(nIRBV)患者的创伤类型、损伤特征、生命体征和结局,并研究IRBV和既往肾功能不全是否会影响院内肾脏并发症(iHRC)的发生可能性。

材料与方法

在国家创伤数据库中识别出有IRBV的穿透性和钝性创伤受害者后,对患者的人口统计学特征、损伤相关变量、治疗结局和护理期间的死亡情况进行分析和比较。

结果

在994184名创伤受害者中,610人(0.6%)发生了IRBV。IRBV组(IRBVG)的穿透性损伤发生率显著更高(19.5%对9.2%,P<0.001),损伤严重程度评分更高(ISS≥25,61.5%对6.7%)。两组中的大多数损伤都是无意的,尽管IRBVG中袭击的发生率更高。IRBVG中iHRC的发生率高于nIRBVG(6.6%对0.4%;P<0.001)。发现IRBV{OR=3.5[95%CI=(2.4-5.0)]}、既往肾脏疾病{OR=2.5[95%CI=(2.1-2.9)]}和院内心脏骤停{OR=8.6[95%CI=(7.7-9.5)]}是与iHRC风险较高相关的因素。

结论

IRBV和既往肾脏疾病显著增加了发生iHRC的风险。由于相关心血管、肾脏和血流动力学并发症的长期和短期后果,IRBV受害者需要专门的肾脏管理和密切监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2800/10264777/62551f61b5ce/fsurg-10-1134945-g001.jpg

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