[心脏压塞作为多发性骨髓瘤的首发表现：一例病例报告并文献复习]

[Cardiac tamponade as first manifestation of multiple myeloma : A case report with literature review].

作者信息

Loukhnati Mehdi, Lahlimi Fatima Ezzahra, Tazi Illias

机构信息

Service d'hématologie clinique et greffe de moelle, CHU Mohammed VI, Université Cadi Ayyad, Marrakech, Maroc.

Service d'hématologie clinique et greffe de moelle osseuse, CHU Mohammed VI, Université Cadi Ayyad, Marrakech, Maroc.

出版信息

Ann Cardiol Angeiol (Paris). 2023 Oct;72(4):101613. doi: 10.1016/j.ancard.2023.101613. Epub 2023 Jun 14.

DOI:10.1016/j.ancard.2023.101613

PMID:37327729

Abstract

Multiple myeloma is a hematologic malignancy characterized by clonal proliferation of plasma cells, mainly in bone marrow. Extramedullary disease is reported in many cases and may occur at diagnosis, at progression, or during relapse phase. Pericardial involvement is a rare condition that usually occurs with advanced-stage disease. We report a rare case of 76-year-old women with plasma cell-based pericardial effusion with cardiac tamponade as a form of presentation of multiple myeloma and discuss it in the light of literature. Diagnosis was established by pericardial fluid cytology. The patient received systemic chemotherapy, according to MPT protocol.

摘要

多发性骨髓瘤是一种血液系统恶性肿瘤，其特征为浆细胞克隆性增殖，主要发生于骨髓。许多病例报告了髓外疾病，可在诊断时、疾病进展期或复发期出现。心包受累是一种罕见情况，通常发生于晚期疾病。我们报告了一例76岁女性的罕见病例，其以浆细胞性心包积液伴心脏压塞作为多发性骨髓瘤的一种表现形式，并结合文献进行讨论。通过心包液细胞学检查确诊。患者根据MPT方案接受了全身化疗。