Maurer R, Schmid U, Davies J D, Mahy N J, Stansfeld A G, Lukes R J
Histopathology. 1986 Jun;10(6):571-88. doi: 10.1111/j.1365-2559.1986.tb02511.x.
A multicentre study of 51 cases of lymph-node infarction seen in the 30-year period 1956 to 1985 was conducted in order to assess both the short- and long-term prognostic implications of the condition. In 14 cases malignant lymphoma was found synchronously with the infarct. Of the remaining 37 patients with apparently 'benign' lymph-node infarction only six showed manifestations of malignant lymphoma in the follow-up time studied (mean = 48 months; range 1-156 months). These subsequent malignant lymphomas all occurred within 2 years of the lymph-node infarction. A postal enquiry and collation of other cases in the medical literature indicates that a minority (26 of 81) have developed malignant lymphoma, and that these lymphomas, too, have all appeared within 2 years. Thorough examination of both the infarcted lymph nodes and others resected at the same time is mandatory in order to exclude concomitant or underlying malignant lymphoma. Two years after lymph-node infarction the risk of malignant lymphoma is negligible.
为评估淋巴结梗死的短期和长期预后影响，我们开展了一项多中心研究，该研究纳入了1956年至1985年这30年间所见的51例淋巴结梗死病例。在14例病例中，恶性淋巴瘤与梗死同时被发现。在其余37例明显为“良性”淋巴结梗死的患者中，在研究的随访期内（平均48个月；范围1 - 156个月）只有6例出现了恶性淋巴瘤的表现。这些后续发生的恶性淋巴瘤均在淋巴结梗死的2年内出现。通过对医学文献中其他病例进行邮政问询和整理发现，少数病例（81例中的26例）发生了恶性淋巴瘤，并且这些淋巴瘤也均在2年内出现。为排除合并存在或潜在的恶性淋巴瘤，对梗死的淋巴结以及同时切除的其他淋巴结进行全面检查是必不可少的。淋巴结梗死2年后发生恶性淋巴瘤的风险可忽略不计。
