Okuni Marika, Yakushijin Kimikazu, Sakai Yasuhiro, Suto Hirotaka, Ichikawa Hiroya, Sakai Rina, Kakiuchi Seiji, Kurata Keiji, Mizutani Yu, Kitao Akihito, Miyata Yoshiharu, Saito Yasuyuki, Kawamoto Shinichiro, Yamamoto Katsuya, Ito Mitsuhiro, Matsuoka Hiroshi, Minami Hironobu
The Division of Medical Oncology and Hematology, the Department of Medicine, Kobe University Hospital, Kobe, Japan.
Department of Diagnostic Pathology, Kobe University Hospital, Kobe, Japan.
J Clin Exp Hematop. 2018 Mar 16;58(1):24-26. doi: 10.3960/jslrt.17026. Epub 2018 Feb 8.
Lymph node infarction is very rare, and is frequently associated with neoplasms, such as malignant lymphoma and non-neoplastic disease, or interventions such as fine-needle aspiration (FNA). A 76-year-old-man presented with cervical lymph node swelling. Although FNA was performed, the findings were insufficient for a definitive diagnosis. Consequently, surgical biopsy of the cervical lymph node was performed, which revealed total infarction; a diagnosis of classical Hodgkin lymphoma was made later. Both lymphoma itself and FNA may cause total lymph node infarction, which makes diagnosis confusing. Therefore, it is important to repeat the biopsy rather than repeat FNA to correctly diagnose malignant lymphoma, including Hodgkin lymphoma.
淋巴结梗死非常罕见,常与肿瘤(如恶性淋巴瘤)、非肿瘤性疾病或诸如细针穿刺抽吸(FNA)等干预措施相关。一名76岁男性出现颈部淋巴结肿大。尽管进行了FNA,但结果不足以明确诊断。因此,对颈部淋巴结进行了手术活检,结果显示为完全梗死;后来诊断为经典型霍奇金淋巴瘤。淋巴瘤本身和FNA都可能导致淋巴结完全梗死,这使得诊断变得混乱。因此,重要的是重复活检而不是重复FNA,以正确诊断包括霍奇金淋巴瘤在内的恶性淋巴瘤。