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胸主动脉腹主动脉瘤的紧急血管内治疗选择。

Emergent endovascular treatment options for thoracoabdominal aortic aneurysm.

机构信息

Department of Vascular Medicine, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Division of Vascular Surgery, Department of Clinical and Experimental Sciences, University of Brescia School of Medicine, ASST Spedali Civili of Brescia, Brescia, Italy.

出版信息

Semin Vasc Surg. 2023 Jun;36(2):174-188. doi: 10.1053/j.semvascsurg.2023.04.004. Epub 2023 Apr 13.

Abstract

For a long time, parallel grafting, physician-modified endografts, and, more recently, in situ fenestration were the only go-to endovascular options for ruptured thoracoabdominal aortic aneurysm, offered mixed results, and depended mainly on the operator's and center's experience. As custom-made devices have become an established endovascular treatment option for elective thoracoabdominal aortic aneurysm, they are not a viable option in the emergency setting, as endograft production can take up to 4 months. The development of off-the-shelf (OTS) multibranched devices with a standardized configuration has allowed the treatment of ruptured thoracoabdominal aortic aneurysm with emergent branched endovascular procedures. The Zenith t-Branch device (Cook Medical) was the first readily available graft outside the United States to receive the CE mark (in 2012) and is currently the most studied device for those indications. A new device, the E-nside thoracoabdominal branch endoprosthesis OTS multibranched endograft (Artivion), has been made commercially available, and the GORE EXCLUDER thoracoabdominal branch endoprosthesis OTS multibranched endograft (W. L. Gore and Associates) is expected to be released in 2023. Due to the lack of guidelines on ruptured thoracoabdominal aortic aneurysm, this review summarizes the available treatment options (ie, parallel grafts, physician-modified endografts, in situ fenestrations, and OTS multibranched devices), compares the indications and contraindications, and points out the evidence gaps that should be filled in the next decade.

摘要

在很长一段时间里,对于破裂性胸腹主动脉瘤,腔内治疗的唯一选择是平行移植物、医师修饰的覆膜支架和最近出现的原位开窗技术,这些方法效果不一,主要取决于术者和中心的经验。随着定制器械已成为治疗择期胸腹主动脉瘤的一种成熟的腔内治疗选择,在紧急情况下,它们不是可行的选择,因为移植物生产可能需要长达 4 个月的时间。现成的(OTS)多分支器械的发展具有标准化配置,允许使用紧急分支腔内手术治疗破裂性胸腹主动脉瘤。Zenith t-Branch 装置(库克医疗)是美国以外第一个获得 CE 标志(2012 年)的现成移植物,目前是这些适应证中研究最多的器械。一种新的装置,E-nside 胸腹分支支架 OTS 多分支覆膜支架(Artivion)已经商业化,GORE EXCLUDER 胸腹分支支架 OTS 多分支覆膜支架(戈尔公司)预计将于 2023 年推出。由于缺乏破裂性胸腹主动脉瘤的指南,这篇综述总结了现有的治疗选择(即平行移植物、医师修饰的覆膜支架、原位开窗和 OTS 多分支装置),比较了适应证和禁忌证,并指出了在下一个十年中应填补的证据空白。

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