Couture L, Chagnon M, Allard C, Bouchard C
Hum Genet. 1986 Jul;73(3):276. doi: 10.1007/BF00401244.
Red blood cell esterase D (ESD) polymorphism was studied in a French-Canadian population from Quebec city, Canada, by means of high voltage electrophoresis on agarose gel followed, in heterozygotes for ESD 1, by IEF to reveal the possible allele ESD5. Frequencies of the ESD alleles in 904 unrelated individuals were ESD1: 0.888, EDS2: 0.095 and ESD5: 0.017. The segregation pattern observed in 275 families confirmed a Mendelian inheritance of three autosomal alleles.
采用琼脂糖凝胶高压电泳法对来自加拿大魁北克市的法裔加拿大人群的红细胞酯酶D(ESD)多态性进行了研究,对于ESD 1杂合子,随后通过等电聚焦电泳(IEF)来揭示可能的等位基因ESD5。在904名无亲缘关系个体中,ESD等位基因的频率分别为:ESD1:0.888,ESD2:0.095,ESD5:0.017。在275个家庭中观察到的分离模式证实了这三个常染色体等位基因的孟德尔遗传。