Department of Internal Medicine, Japan.
Department of Internal Medicine, Japan.
Respir Investig. 2023 Sep;61(5):548-552. doi: 10.1016/j.resinv.2023.05.003. Epub 2023 Jun 16.
Here, we report a case of idiopathic pleuroparenchymal fibroelastosis (PPFE) that progressed to pulmonary aspergilloma, aspiration pneumonia, and left vocal cord paralysis (VCP). To date, five cases of PPFE with VCP have been reported, including the present case. Aspiration pneumonia occurred in three cases, leading to death in two cases. Four cases had left-sided paralysis, in two of which, the paralysis occurred on side opposite to the predominant side (right side) of PPFE. Structural mechanisms underlying the recurrent laryngeal nerve could be involved. This report may further highlight the existence of hoarseness and dysphagia in PPFE.
在这里，我们报告一例特发性胸膜肺弹力纤维增生症（PPFE）进展为肺曲霉球、吸入性肺炎和左侧声带麻痹（VCP）。迄今为止，已有 5 例伴有 VCP 的 PPFE 病例报告，包括本病例。3 例发生吸入性肺炎，其中 2 例导致死亡。4 例出现左侧麻痹，其中 2 例麻痹发生在与 PPFE 优势侧（右侧）相反的一侧。可能涉及喉返神经的结构机制。本报告可能进一步强调 PPFE 存在声音嘶哑和吞咽困难。
