Hirano M, Tanaka S, Fujita M, Fujita H
Department of Otolaryngology-Head and Neck Surgery, Kurume University, Japan.
Ann Otol Rhinol Laryngol. 1993 Mar;102(3 Pt 1):182-5. doi: 10.1177/000348949310200304.
Esophageal cancer surgery was the cause of paralysis in 111 (16.7%) of 664 patients with vocal cord paralysis seen from 1981 to 1990 at Kurume University Hospital. Eighty-six patients had unilateral paralysis, whereas 25 had bilateral lesions. Of the 111, 95 (86%) had hoarseness and 59 (53%) had aspiration. The crude survival rate was 63% for 1-year, 32% for 3-year, and 22% for 5-year follow-up. The average life expectancy was short. The general condition was poor in many patients. Thirty-four of the 136 paralytic vocal cords (25%) recovered mobility. An intracordal silicone injection was done in 30 patients, and a medialization procedure was performed in 1. The vocal function was improved in the majority of cases. In 4 patients, severe aspiration persisted following intracordal injection. Of the 4, 1 had cricopharyngeal myotomy and laryngeal suspension and 2 underwent total laryngectomy. The fourth patient died of aspiration pneumonia. The results of the review of the 111 patients have led us to the following treatment policy for patients with vocal cord paralysis caused by esophageal cancer surgery. When the patient has aspiration, vocal cord medialization should be performed as early as possible. If severe aspiration persists even after the medialization procedure, some additional intervention, including cricopharyngeal myotomy, laryngeal suspension, laryngotracheal separation, or total laryngectomy, should be considered. When hoarseness is the only major problem, the prognosis of vocal cord paralysis should be determined on the basis of the state of the recurrent laryngeal nerve and, if available, electromyography findings.(ABSTRACT TRUNCATED AT 250 WORDS)
1981年至1990年期间,久留米大学医院收治的664例声带麻痹患者中,111例(16.7%)的病因是食管癌手术。86例为单侧麻痹,25例为双侧病变。在这111例患者中,95例(86%)声音嘶哑,59例(53%)存在误吸。1年随访的粗生存率为63%,3年为32%,5年为22%。平均预期寿命较短。许多患者的一般状况较差。136条麻痹声带中有34条(25%)恢复了活动能力。30例患者进行了声带内硅胶注射,1例进行了声带内移手术。大多数病例的发声功能得到改善。4例患者在声带内注射后仍存在严重误吸。这4例患者中,1例行环咽肌切开术和喉悬吊术,2例行全喉切除术。第4例患者死于误吸性肺炎。对这111例患者的回顾结果使我们得出了针对食管癌手术所致声带麻痹患者的以下治疗策略。当患者有误吸时,应尽早进行声带内移。如果在内移手术后仍存在严重误吸,则应考虑一些额外的干预措施,包括环咽肌切开术、喉悬吊术、喉气管分离术或全喉切除术。当声音嘶哑是唯一的主要问题时,应根据喉返神经的状态以及(如有)肌电图检查结果来判断声带麻痹的预后。(摘要截选至250字)