Division of Rheumatology, University of California Los Angeles, 2020 Santa Monica Boulevard, Suite 540, Santa Monica, CA 90404, USA.
Division of Rheumatology and Immunology, Vanderbilt University Medical Center, 1161 21st Avenue South, T3113, MCN, Nashville, TN 37232, USA.
Rheum Dis Clin North Am. 2023 Aug;49(3):523-543. doi: 10.1016/j.rdc.2023.03.013. Epub 2023 Apr 28.
The finding of aortitis, often incidentally noted on surgical resection, should prompt evaluation for secondary causes including large-vessel vasculitis. In a large proportion of cases, no other inflammatory cause is identified and the diagnosis of clinically isolated aortitis is made. It is unknown whether this entity represents a more localized form of large-vessel vasculitis. The need for immunosuppressive therapy in patients with clinically isolated aortitis remains unclear. Patients with clinically isolated aortitis warrant imaging of the entire aorta at baseline and regular intervals because a significant proportion of patients have or develop abnormalities in other vascular beds.
主动脉炎的发现常常是在外科切除时偶然发现的，应提示评估继发性病因，包括大血管血管炎。在很大一部分病例中，未发现其他炎症性病因，诊断为临床孤立性主动脉炎。目前尚不清楚这种情况是否代表一种更局限的大血管血管炎形式。在临床上孤立性主动脉炎患者中是否需要免疫抑制治疗仍不清楚。临床上孤立性主动脉炎患者需要在基线和定期进行整个主动脉的影像学检查，因为很大一部分患者存在或发展为其他血管床的异常。
