Raizada Amit, Trivedi Dhaval
Internal Medicine, New York Presbyterian Brooklyn Methodist Hospital, New York City, USA.
Cureus. 2024 Jun 28;16(6):e63415. doi: 10.7759/cureus.63415. eCollection 2024 Jun.
Aortitis is a general term that describes inflammation of the aorta. In most cases, this inflammation is caused by an autoimmune etiology or an infectious etiology. In some instances, the underlying etiology may not be clear, and the diagnosis given is idiopathic aortitis. Cases of idiopathic aortitis are usually diagnosed based on histopathologic findings. Here, we present a case involving a 31-year-old female presenting with acutely worsening exertional shortness of breath and left-sided chest pain. An echocardiogram revealed a severely reduced ejection fraction with severe aortic regurgitation and diffusely increased aortic intima-media thickness. Bioprosthetic aortic valve replacement was performed with histology, showing findings consistent with aortitis, and the patient received the diagnosis of idiopathic aortitis. This case highlights the need to consider aortitis as a differential in young patients presenting with exertional chest pain and severe aortic insufficiency.
主动脉炎是一个描述主动脉炎症的通用术语。在大多数情况下，这种炎症是由自身免疫病因或感染病因引起的。在某些情况下，潜在病因可能不明确，所给出的诊断为特发性主动脉炎。特发性主动脉炎病例通常根据组织病理学发现进行诊断。在此，我们报告一例31岁女性病例，该患者出现劳力性呼吸困难急性加重和左侧胸痛。超声心动图显示射血分数严重降低，伴有严重主动脉反流，主动脉内膜中层厚度弥漫性增加。进行了生物人工主动脉瓣置换术，组织学检查结果与主动脉炎一致，该患者被诊断为特发性主动脉炎。该病例强调了在出现劳力性胸痛和严重主动脉瓣关闭不全的年轻患者中，需要将主动脉炎作为鉴别诊断的考虑因素。
