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儿童多系统炎症综合征与川崎病:一类感染后过度炎症性疾病。

Multisystem Inflammatory Syndrome in Children and Kawasaki Disease: A Spectrum of Postinfectious Hyperinflammatory Disease.

机构信息

Department of Medicine, Pediatric Rheumatology, Hospital for Special Surgery, New York, NY, USA; Department of Pediatric Rheumatology, 535 East 70th Street, New York, NY 10021, USA.

Department of Pediatrics, Columbia University Medical Center, New York, NY, USA; Morgan Stanley Children's Hospital, 3959 Broadway Central 5th Floor, New York, NY 10032, USA.

出版信息

Rheum Dis Clin North Am. 2023 Aug;49(3):661-678. doi: 10.1016/j.rdc.2023.03.003. Epub 2023 Apr 15.

DOI:10.1016/j.rdc.2023.03.003
PMID:37331739
Abstract

Kawasaki disease and multisystem inflammatory syndrome in children are hyperinflammatory conditions that share similar emerging pathophysiology hypotheses, clinical features, treatment strategies, and outcomes. Although both conditions have key differences, growing evidence suggests that both conditions might be closely related on a larger spectrum of postinfectious autoimmune responses.

摘要

川崎病和儿童多系统炎症综合征是两种高炎症性疾病,它们具有相似的新兴病理生理学假说、临床特征、治疗策略和结局。尽管这两种疾病有明显的区别,但越来越多的证据表明,这两种疾病可能在更大程度的感染后自身免疫反应谱上密切相关。

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