Matériaux et Santé, UFR de pharmacie, Université Paris Saclay, France.
Matériaux et Santé, UFR de pharmacie, Université Paris Saclay, France.
Med Eng Phys. 2023 Jul;117:103994. doi: 10.1016/j.medengphy.2023.103994. Epub 2023 May 17.
The impact of ethanol locks on the mechanical performances of central venous catheters was compared to that of aqueous-based locks. Several mechanical tests were performed to evaluate catheter behavior: kinking radius measurements, burst pressure, and tensile tests. Different polyurethanes were studied to assess the impact of radio-opaque charge and polymer chemical composition on catheter behavior. The results were correlated to swelling measurements and calorimetric measurements. In particular, ethanol locks have a higher impact on long contact time than aqueous-based locks: stresses and strains at break were lower, and kinking radii were higher. However, for all catheters, the mechanical performances remain much higher than the normative requirements.
将乙醇锁定对中心静脉导管的机械性能的影响与基于水的锁定进行了比较。进行了几项机械测试来评估导管的行为：扭结半径测量、爆破压力和拉伸测试。研究了几种不同的聚氨酯，以评估放射状电荷和聚合物化学成分对导管行为的影响。结果与溶胀测量和量热测量相关联。特别是，乙醇锁定对长接触时间的影响高于基于水的锁定：断裂时的应力和应变较低，扭结半径较高。然而，对于所有导管，机械性能仍然远高于规范要求。
