[The biochemical activity of the aflatoxins (author's transl)].
作者信息
Reiss J
出版信息
Zentralbl Bakteriol B. 1978 Dec;167(5-6):435-42.
PMID:373323
Abstract
Results of experiments with the Salmonella typhimurium-liver microsome technique make it evident that the mutagenic and carcinogenic metabolite of aflatoxin B1 is aflatoxin B1-2,3-oxide. This compound forms adducts with guanine in DNA. There is a close relationship between the mutagenic activity and the hepatocarcinogenic property of the different aflatoxin derivatives.
摘要
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