• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

紫外线照射后黄曲霉毒素诱变活性的降低。

Reduction of mutagenic activity of aflatoxins after UV-irradiation.

作者信息

Kleinwächter V, Koukalová B

出版信息

Acta Biol Med Ger. 1979;38(9):1239-42.

PMID:399142
Abstract

Solutions of aflatoxins B1, B2, G1 and G2 and solid films of aflatoxin B1 were irradiated with UV light of wavelength corresponding to the absorption band of aflatoxins at approximately 365 nm (approximately 27 500 cm-1). The reaction was followed spectrophotometrically. Simultaneously the mutagenicity of samples of aflatoxins was determined using Salmonella typhimurium/mammalian microsome test. UV-irradiation caused a modification in all aflatoxins studied (in aqueous and nonaqueous solutions as well as in a solid film); the final photoproducts lost completely the mutagenic activity.

摘要

用波长约为365nm(约27500cm-1)、对应黄曲霉毒素吸收带的紫外光照射黄曲霉毒素B1、B2、G1和G2的溶液以及黄曲霉毒素B1的固体薄膜。通过分光光度法跟踪反应。同时,使用鼠伤寒沙门氏菌/哺乳动物微粒体试验测定黄曲霉毒素样品的诱变性。紫外线照射使所有研究的黄曲霉毒素(在水溶液和非水溶液以及固体薄膜中)发生了变化;最终的光产物完全丧失了诱变活性。

相似文献

1
Reduction of mutagenic activity of aflatoxins after UV-irradiation.紫外线照射后黄曲霉毒素诱变活性的降低。
Acta Biol Med Ger. 1979;38(9):1239-42.
2
The mutagenicity of aflatoxin Q1 to Salmonella typhimurium TA 100 with or without rat or human liver microsomal preparations.黄曲霉毒素Q1在有或无大鼠或人肝微粒体制剂存在的情况下对鼠伤寒沙门氏菌TA 100的致突变性。
Res Commun Chem Pathol Pharmacol. 1986 Oct;54(1):101-13.
3
Comparative mutagenicity of palmotoxin Bo and aflatoxins B1 and M1.棕榈毒素Bo与黄曲霉毒素B1和M1的比较致突变性。
J Environ Pathol Toxicol. 1979 Mar-Apr;2(4):1099-107.
4
Stereochemical effect in the mutagenicity of the aflatoxicols toward Salmonella typhimurium.黄曲霉毒素醇对鼠伤寒沙门氏菌致突变性中的立体化学效应。
Life Sci. 1987 Oct 12;41(15):1795-803. doi: 10.1016/0024-3205(87)90698-9.
5
Mutagenicity of chemicals produced from sodium dodecylbenzenesulfonate by treatment with ozone and ultraviolet irradiation.
Tokushima J Exp Med. 1996 Jun;43(1-2):47-54.
6
Mutagenicity of aflatoxins related to their metabolism and carcinogenic potential.黄曲霉毒素的致突变性与其代谢及致癌潜力相关。
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2241-4. doi: 10.1073/pnas.73.7.2241.
7
[Changes in the mutagenic effect of a medium containing aflatoxin B1 as a result of the yeast activity].[酵母活性对含黄曲霉毒素B1培养基致突变作用的影响]
Gig Sanit. 1990 Dec(12):45-7.
8
The reduced mutagenicity of aflatoxin B1 due to hydroxylation: observations on five Salmonella typhimurium tester strains.黄曲霉毒素B1因羟基化导致的致突变性降低:对五株鼠伤寒沙门氏菌测试菌株的观察
Cancer Lett. 1979 Aug;7(4):221-5. doi: 10.1016/s0304-3835(79)80084-1.
9
Photoactivated aflatoxins are mutagens to Salmonella typhimurium and bind covalently to DNA in vitro.光活化黄曲霉毒素对鼠伤寒沙门氏菌具有致突变性,并在体外与DNA共价结合。
Carcinogenesis. 1982;3(4):423-9. doi: 10.1093/carcin/3.4.423.
10
The direct mutagenicity of aflatoxin B1 and metabolites to Salmonella typhimurium: structure mutagenicity relationships and mechanisms of action.黄曲霉毒素B1及其代谢产物对鼠伤寒沙门氏菌的直接致突变性:结构-致突变性关系及作用机制
Res Commun Chem Pathol Pharmacol. 1987 Jul;57(1):55-76.