Basanoo Laéshelle S, Bahall Vishal, Mohammed Salma, Teelucksingh Shravan
Intensive Care Unit / Anaesthetic Department, Sangre Grande Hospital, Sangre Grande, TTO.
Obstetrics and Gynaecology, The University of the West Indies, St Augustine, TTO.
Cureus. 2023 May 16;15(5):e39101. doi: 10.7759/cureus.39101. eCollection 2023 May.
Uterine leiomyosarcomas are an extremely rare subtype of uterine malignancy. This is a case report of a 47-year-old woman whose underlying uterine leiomyosarcoma manifested as acute respiratory distress secondary to pulmonary metastases. We highlight that a combination of suggestive imaging features and elevated lactate dehydrogenase (LDH) may prompt its diagnosis, notwithstanding that histological examination of a tissue sample is mandatory for its confirmation. The diagnosis of this condition is arduous for a multitude of reasons, including the insidious clinical course, aggressive nature, and high propensity to metastasize, coupled with a lack of standardised guidelines for its preoperative work-up. These challenges are amplified where resources may be limited, such as in the Caribbean region, where radiographic imaging and treatment options may not always be readily available.
子宫平滑肌肉瘤是一种极其罕见的子宫恶性肿瘤亚型。本文报告一例47岁女性病例，其潜在的子宫平滑肌肉瘤表现为继发于肺转移的急性呼吸窘迫。我们强调，尽管组织样本的组织学检查是确诊的必要条件，但提示性的影像学特征和乳酸脱氢酶（LDH）升高相结合可能有助于其诊断。由于多种原因，这种疾病的诊断很困难，包括隐匿的临床病程、侵袭性本质、高转移倾向，以及缺乏术前检查的标准化指南。在资源可能有限的地区，如加勒比地区，这些挑战会更加突出，因为那里的放射影像学检查和治疗选择可能并不总是容易获得。
