Liu Junxiu, Wang Zijie
Department of Obstetrics and Gynecology, The Affiliated Hospital of Qingdao University, Qingdao 266000, China.
Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao 266000, China.
Cancers (Basel). 2022 Jul 20;14(14):3517. doi: 10.3390/cancers14143517.
Uterine sarcomas are rare malignant tumors of the uterus with a high degree of malignancy. Their clinical manifestations, imaging examination findings, and laboratory test results overlap with those of uterine fibroids. No reliable diagnostic criteria can distinguish uterine sarcomas from other uterine tumors, and the final diagnosis is usually only made after surgery based on histopathological evaluation. Conservative or minimally invasive treatment of patients with uterine sarcomas misdiagnosed preoperatively as uterine fibroids will shorten patient survival. Herein, we will summarize recent advances in the preoperative diagnosis of uterine sarcomas, including epidemiology and clinical manifestations, laboratory tests, imaging examinations, radiomics and machine learning-related methods, preoperative biopsy, integrated model and other relevant emerging technologies.
子宫肉瘤是子宫罕见的恶性肿瘤，恶性程度高。其临床表现、影像学检查结果和实验室检查结果与子宫肌瘤重叠。尚无可靠的诊断标准能将子宫肉瘤与其他子宫肿瘤区分开来，最终诊断通常仅在手术后根据组织病理学评估做出。对术前被误诊为子宫肌瘤的子宫肉瘤患者进行保守或微创治疗会缩短患者生存期。在此，我们将总结子宫肉瘤术前诊断的最新进展，包括流行病学和临床表现、实验室检查、影像学检查、放射组学和机器学习相关方法、术前活检、综合模型及其他相关新兴技术。
