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择期胸主动脉瘤手术:一家三级中心的经验

Elective Thoracic Aortic Aneurysm Surgery: A Tertiary Center Experience.

作者信息

Badran Abdul, Elghazouli Youssef, Shirke Manasi Mahesh, Al-Tawil Mohammed, Harky Amer, Ohri Sunil K

机构信息

Cardiothoracic Surgery, Southampton General Hospital NHS Foundation Trust, Southampton, GBR.

Medicine, Queen's University Belfast, Belfast, GBR.

出版信息

Cureus. 2023 May 16;15(5):e39102. doi: 10.7759/cureus.39102. eCollection 2023 May.

DOI:10.7759/cureus.39102
PMID:37332465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10270669/
Abstract

Background A thoracic aortic aneurysm (TAA) is a diseased expansion of the thoracic aorta. There is morbidity associated with a dilated aorta, as well as significant mortality. Open thoracic surgery is the fundamental management for proximal lesions, offering definitive treatment with excellent results. This study aimed to summarize preoperative data and operative outcomes of patients who underwent TAA repair at our institution. Methods Data were retrospectively collected from 234 patients that underwent elective open thoracic surgery at University Hospital Southampton for TAA disease, between 2015 and 2019. Demographics, clinical factors, surgical details, as well as outcome measures, were gathered. Results There were 166 males and 68 females, with an overall mean age of 66 years. The breakdown of operations comprised 105 aortic roots, 171 ascending aorta, 20 aortic arch, and 12 descending aorta cases. The mean follow-up was 370 days. 30-day mortality was 5.13%. Mortality was associated with female gender, aortic root surgery, and prosthetic valves. Mean aortic diameters at the time of surgery for the non-genetic aortopathy and genetic aortopathy groups were respectively 4.93cm and 4.63cm in the aortic root, 5.56cm and 4.88cm in the ascending aorta, 5.08cm and 3.87cm in the aortic arch, and 6.63cm and 5.50cm in the descending aorta. Conclusion Several factors are associated with complications and morbidity, which should be considered when discussing the risks of intervention with patients. There were no neuroprotective strategies that altered post-operative neurological function. Current practice in our unit fits in with current international guidance.

摘要

背景

胸主动脉瘤(TAA)是胸主动脉的病理性扩张。主动脉扩张会导致发病,同时死亡率也很高。开放性胸外科手术是近端病变的基本治疗方法,能提供确定性治疗且效果良好。本研究旨在总结在我们机构接受TAA修复患者的术前数据和手术结果。

方法

回顾性收集2015年至2019年间在南安普敦大学医院因TAA疾病接受择期开放性胸外科手术的234例患者的数据。收集了人口统计学、临床因素、手术细节以及结果指标。

结果

男性166例,女性68例,总体平均年龄为66岁。手术分类包括105例主动脉根部、171例升主动脉、20例主动脉弓和12例降主动脉病例。平均随访时间为370天。30天死亡率为5.13%。死亡率与女性性别、主动脉根部手术和人工瓣膜有关。非遗传性主动脉病变组和遗传性主动脉病变组手术时主动脉根部的平均直径分别为4.93cm和4.63cm,升主动脉分别为5.56cm和4.88cm,主动脉弓分别为5.08cm和3.87cm,降主动脉分别为6.63cm和5.50cm。

结论

有几个因素与并发症和发病率相关,在与患者讨论干预风险时应予以考虑。没有神经保护策略能改变术后神经功能。我们科室目前的做法符合当前国际指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/52de5332bf38/cureus-0015-00000039102-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/21e615f5c6ea/cureus-0015-00000039102-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/5b2050167821/cureus-0015-00000039102-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/eec679dc1108/cureus-0015-00000039102-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/11cb7fcfd342/cureus-0015-00000039102-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/39955bdf52fd/cureus-0015-00000039102-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/3c7a0a669974/cureus-0015-00000039102-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/c8e863320f9f/cureus-0015-00000039102-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/0e219e45e54a/cureus-0015-00000039102-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/52de5332bf38/cureus-0015-00000039102-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/21e615f5c6ea/cureus-0015-00000039102-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/5b2050167821/cureus-0015-00000039102-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/eec679dc1108/cureus-0015-00000039102-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/11cb7fcfd342/cureus-0015-00000039102-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/39955bdf52fd/cureus-0015-00000039102-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/3c7a0a669974/cureus-0015-00000039102-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/c8e863320f9f/cureus-0015-00000039102-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/0e219e45e54a/cureus-0015-00000039102-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa1c/10270669/52de5332bf38/cureus-0015-00000039102-i09.jpg

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