Hashimoto Yuiko, Teshima Masanori, Yui Mitsuko, Tatehara Shun, Iritani Keisuke, Furukawa Tatsuya, Shinomiya Hirotaka, Nibu Ken-Ichi
Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-Cho, Chuo-Ku, Kobe, Hyogo, 650-0017, Japan.
J Surg Case Rep. 2023 Jun 15;2023(6):rjad310. doi: 10.1093/jscr/rjad310. eCollection 2023 Jun.
Chylous leakage is a rare but serious postoperative complication of neck dissection (ND). Most chylous leakages are successfully treated either by drainage or ligation of the thoracic duct, but the resolution is occasionally prolonged. OK432 sclerotherapy is used to treat various refractory cystic diseases of the head and neck. Three patients were treated with OK432 sclerotherapy for refractory chylous leakage following ND. Case 1 involved a 77-year-old man with chylous leakage after a total laryngectomy and bilateral ND. Case 2 involved a 71-year-old woman who underwent total thyroidectomy and left ND for thyroid cancer. Case 3 involved a 61-year-old woman who underwent right ND for oropharyngeal cancer. In all patients, chylous leakage rapidly improved after OK432 injection without any complications. Our results suggest the efficacy of OK432 sclerotherapy in patients with refractory chylous leakage after ND.
乳糜漏是颈部清扫术（ND）一种罕见但严重的术后并发症。大多数乳糜漏通过胸导管引流或结扎得以成功治疗，但有时恢复过程会延长。OK432硬化疗法用于治疗头颈部各种难治性囊性疾病。3例患者接受了OK432硬化疗法治疗ND术后难治性乳糜漏。病例1为一名77岁男性，全喉切除及双侧颈部清扫术后出现乳糜漏。病例2为一名71岁女性，因甲状腺癌接受全甲状腺切除及左侧颈部清扫术。病例3为一名61岁女性，因口咽癌接受右侧颈部清扫术。所有患者在注射OK432后乳糜漏迅速改善，且无任何并发症。我们的结果表明OK432硬化疗法对ND术后难治性乳糜漏患者有效。
