Grazioso Tatiana P, Djouder Nabil
Molecular Oncology Programme, Growth Factors, Nutrients and Cancer Group, Centro Nacional de Investigaciones Oncológicas, CNIO, ES-28029 Madrid, Spain.
Gynecological, Genitourinary and Skin Cancer Unit HM, Clara Campal Comprehensive Cancer Center, CIOCC, Department of Basic Medical Sciences, Hospital Universitario HM Sanchinarro, ES-28050 Madrid, Spain.
iScience. 2023 May 29;26(7):107010. doi: 10.1016/j.isci.2023.107010. eCollection 2023 Jul 21.
Cold therapy has been used for centuries, from Julius Caesar to Mohandas Gandhi, as a potent therapeutic approach. However, it has been largely forgotten in modern medicine. This review explores the history of cold therapy and its potential application as a therapeutic strategy against various diseases, including cancer. We examine the different techniques of cold exposure and the use of other therapeutical approaches, such as , and delivery of . While clinical trials using cold therapy for cancer treatment are still limited, recent research shows promising results in experimental animal cancer models. This area of research is becoming increasingly significant and warrants further investigation.
几个世纪以来，从尤利乌斯·恺撒到莫罕达斯·甘地，冷疗法一直作为一种有效的治疗方法被使用。然而，它在现代医学中很大程度上已被遗忘。这篇综述探讨了冷疗法的历史及其作为对抗包括癌症在内的各种疾病的治疗策略的潜在应用。我们研究了不同的冷暴露技术以及其他治疗方法的使用，例如，和的递送。虽然使用冷疗法治疗癌症的临床试验仍然有限，但最近的研究在实验动物癌症模型中显示出了有希望的结果。这一研究领域正变得越来越重要，值得进一步研究。
