Sun Yan, Meng Fan-Jun, Huang Jun-Xia, Yan Xue-Shen, Zhao Xia, Zhou Jing-Jing, Gao Yan
Department of Hematology, The Affiliated Hospital of Qingdao University, No. 1677 of Wutaishan Road, Huangdao District, Qingdao 266000, Shandong, China.
Open Life Sci. 2023 Jun 14;18(1):20220619. doi: 10.1515/biol-2022-0619. eCollection 2023.
Waldenström macroglobulinemia (WM) rarely leads to pulmonary embolism. Due to its low incidence, the underlying pathophysiology, prognosis, and optimal treatment remain largely unexplored and uninvestigated. In this study, a patient with a double-clonal WM, a rare subtype, presented with pulmonary embolism. The patient had a small number of plasma cells without morphological abnormalities, and an effective therapeutic response was observed. Nonetheless, the clinical prognosis requires a long-term follow-up.
华氏巨球蛋白血症(WM)很少导致肺栓塞。由于其发病率低,其潜在的病理生理学、预后及最佳治疗方法在很大程度上仍未得到探索和研究。在本研究中,一名患有罕见双克隆WM亚型的患者出现了肺栓塞。该患者有少量形态无异常的浆细胞,并观察到有效的治疗反应。尽管如此,临床预后仍需要长期随访。