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伴有肺栓塞的双克隆性华氏巨球蛋白血症罕见病例报告

Rare presentation of double-clonal Waldenström macroglobulinemia with pulmonary embolism: A case report.

作者信息

Sun Yan, Meng Fan-Jun, Huang Jun-Xia, Yan Xue-Shen, Zhao Xia, Zhou Jing-Jing, Gao Yan

机构信息

Department of Hematology, The Affiliated Hospital of Qingdao University, No. 1677 of Wutaishan Road, Huangdao District, Qingdao 266000, Shandong, China.

出版信息

Open Life Sci. 2023 Jun 14;18(1):20220619. doi: 10.1515/biol-2022-0619. eCollection 2023.

Abstract

Waldenström macroglobulinemia (WM) rarely leads to pulmonary embolism. Due to its low incidence, the underlying pathophysiology, prognosis, and optimal treatment remain largely unexplored and uninvestigated. In this study, a patient with a double-clonal WM, a rare subtype, presented with pulmonary embolism. The patient had a small number of plasma cells without morphological abnormalities, and an effective therapeutic response was observed. Nonetheless, the clinical prognosis requires a long-term follow-up.

摘要

华氏巨球蛋白血症(WM)很少导致肺栓塞。由于其发病率低,其潜在的病理生理学、预后及最佳治疗方法在很大程度上仍未得到探索和研究。在本研究中,一名患有罕见双克隆WM亚型的患者出现了肺栓塞。该患者有少量形态无异常的浆细胞,并观察到有效的治疗反应。尽管如此,临床预后仍需要长期随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11c2/10276544/a9df725e0d11/j_biol-2022-0619-fig001.jpg

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