Zaninotto G, Bonavina L, Pianalto S, Fassina A, Ancona E
Int Surg. 1986 Apr-Jun;71(2):100-3.
Esophageal stricture is not reported to be a common complication of nasogastric intubation. Two patients who had a Levin tube inserted in the stomach for nutrition during a prolonged coma, and finally presented with a severe esophageal stricture were observed and treated. The clinical history of the patients suggests that the pathogenesis of this lesion is probably multifactorial, secondary to induced gastroesophageal reflux, impaired esophageal clearance, high gastric acid output, and use of steroids. Jejunostomy feeding, rather than nasogastric feeding, is probably a better means to provide nutritional support in comatose patients, thus averting the risk of such a serious complication. Esophageal replacement with left colon interposition appears the treatment of choice for these severe esophageal strictures.
据报道，食管狭窄并非鼻胃插管的常见并发症。观察并治疗了两名在长期昏迷期间经胃插入 Levin 管进行营养支持，最终出现严重食管狭窄的患者。患者的临床病史表明，该病变的发病机制可能是多因素的，继发于诱发性胃食管反流、食管清除功能受损、胃酸分泌过多以及使用类固醇。对于昏迷患者，空肠造口喂养而非鼻胃喂养可能是提供营养支持的更好方法，从而避免这种严重并发症的风险。对于这些严重的食管狭窄，采用左结肠代食管似乎是首选的治疗方法。
