Ben Rejeb M, Bouché O, Zeitoun P
Department of Hepato-gastroenterology, Hôpital Robert Debré, Reims, France.
Dig Dis Sci. 1992 May;37(5):733-6. doi: 10.1007/BF01296431.
The purpose of this study, making use of systematic records on computer over a period of 12 years, was to compare the prevalence and the demographic characteristics of patients with peptic stricture with those having a reflux esophagitis. As compared with 3880 cases of erosive and/or ulcerative esophagitis, the percentage of peptic stricture patients was 1.21%. The latter were on average nine years older and more frequently had a hiatus hernia. Ten patients with peptic stricture had had severe esophagitis previously recorded in our department. Thirty-four peptic stricture patients (72.3%) had at least one condition reported as possibly provocative of stricture. This study stresses the point that the incidence of peptic esophageal stricture is probably far lower than had been reported previously. Consequently, management of low-grade reflux esophagitis should be aimed primarily at relieving symptoms rather than healing esophageal lesions to prevent stricture.
本研究利用计算机系统记录，在12年的时间里，比较了消化性狭窄患者与反流性食管炎患者的患病率和人口统计学特征。与3880例糜烂性和/或溃疡性食管炎患者相比，消化性狭窄患者的比例为1.21%。后者平均年龄大9岁，且更常患有食管裂孔疝。10例消化性狭窄患者此前在我科有严重食管炎记录。34例消化性狭窄患者（72.3%）至少有一种被报告可能引发狭窄的病症。本研究强调，消化性食管狭窄的发生率可能远低于先前报道的水平。因此，轻度反流性食管炎的治疗应主要旨在缓解症状，而非治愈食管病变以预防狭窄。
