Senthilnathan Subramanian, Jayaraman Selvaraj, Priya Veeraraghavan Vishnu, Masood Khan Javed, Ahmed Mohammad Z, Ahmad Anis, Gnanamani Arumugam
Microbiology Laboratory, CSIR- Central Leather Research Institute, Adyar, Chennai 600020, India.
Centre of Molecular Medicine and Diagnostics (COMManD), Department of Biochemistry, Saveetha Dental College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, Chennai 600077, India.
Saudi J Biol Sci. 2023 Jul;30(7):103700. doi: 10.1016/j.sjbs.2023.103700. Epub 2023 Jun 1.
The Siddha system of medicine is an ancient medical lineage that is practiced primarily in the southern part of India. Siddha system of medicine has been in practice for thousands of years with documented evidence dating back to the 6th century BCE. According to siddha system of medicine's basic fundamental principle, the human body is made up of 96 thathuvam (primary components), which encompass physical, physiological, psychological, and intellectual aspects. Medicine (marunthu) is classified as a wide range of internal and external medicines. The major components of its medical formulations include plant parts, minerals and animal products. Various methods were carried out for the purification process to eliminate the toxins. Choornam, Guligai, Tailam, Parpam, Chendooram, Kattu, Pasai and Poochu are the most common medicines used in Siddha system of medicine for the treatment of various diseases. The pathophysiological classification of diseases is elaborated in detail in the classical Siddha literature. Siddha system of medicine plays an important role in protecting people from diseases such as COVID-19 by providing immune-protecting and immune-boosting medicines in today's world. Mathan tailam and maha megarajanga tailam are the two unique preparations used widely for various skin diseases including chronic wounds and burns. Scientific validation of both medicines will help in understanding their effectiveness against a typical wound condition. In the present study physio-chemical and phytochemical, HPTLC, and GC-MS analyses were carried out and discussed in detail on the multifunctional properties exhibited in the patient communities.
悉达医学体系是一种古老的医学传承，主要在印度南部地区应用。悉达医学体系已经实践了数千年，有文献记载可追溯到公元前6世纪。根据悉达医学体系的基本原理，人体由96种“thathuvam”（主要成分）组成，涵盖身体、生理、心理和智力方面。药物（marunthu）分为多种内服和外用药物。其药物配方的主要成分包括植物部位、矿物质和动物产品。采用了各种方法进行净化过程以去除毒素。“Choornam”、“Guligai”、“Tailam”、“Parpam”、“Chendooram”、“Kattu”、“Pasai”和“Poochu”是悉达医学体系中用于治疗各种疾病的最常见药物。疾病的病理生理分类在经典的悉达文献中有详细阐述。在当今世界，悉达医学体系通过提供免疫保护和增强免疫力的药物，在保护人们免受如COVID - 19等疾病方面发挥着重要作用。“Mathan tailam”和“maha megarajanga tailam”是两种独特的制剂，广泛用于包括慢性伤口和烧伤在内的各种皮肤病。对这两种药物的科学验证将有助于了解它们对典型伤口状况的有效性。在本研究中，对患者群体中表现出的多功能特性进行了物理化学、植物化学、高效薄层色谱（HPTLC）和气相色谱 - 质谱（GC - MS）分析，并进行了详细讨论。
