Kohata Yutaro, Ohta Makoto, Jin Kazuyoshi, Anzai Hitomi
Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan.
Biomedical Flow Dynamics Laboratory, The Institute of Fluid Science, Tohoku University, Sendai, Japan.
Front Med Technol. 2023 Jun 2;5:1196125. doi: 10.3389/fmedt.2023.1196125. eCollection 2023.
As an approach to maintain patency in femoropopliteal stenting, a helical stent configuration was proposed, which showed improved patency in clinical trials. However, the effects of helical stent placement on the flow have not been quantitatively analyzed. The purpose of this study was to estimate flow velocities to quantify the influence of helical stent placement. Helical and straight stents were implanted in three healthy pigs, and the flow velocities were estimated using the time-intensity curve (TIC) in the angiography images. The angiographic images indicated thinning of the leading edge of the contrast medium through the helically deformed artery, which was not observed in the straight stent. The slower rise of the TIC peak in the helical stent indicated faster travel of this thinner edge. Arterial expansion due to stenting was observed in all cases, and the expansion rate varied according to location. All cases of helical stent implantation showed that velocity was maintained (55.0%-71.3% velocity retention), unlike for straight stent implantation (43.0%-68.0% velocity retention); however, no significant difference was observed.
作为一种维持股腘动脉支架通畅性的方法，人们提出了一种螺旋支架构型，该构型在临床试验中显示出更好的通畅性。然而，螺旋支架置入对血流的影响尚未进行定量分析。本研究的目的是估计血流速度，以量化螺旋支架置入的影响。在三只健康猪体内植入螺旋和直形支架，并使用血管造影图像中的时间-强度曲线（TIC）估计血流速度。血管造影图像显示，造影剂前缘通过螺旋形变形动脉时变薄，而在直形支架中未观察到这种情况。螺旋支架中TIC峰值的上升较慢，表明这个较薄边缘的移动速度较快。在所有病例中均观察到由于支架置入导致的动脉扩张，且扩张率因位置而异。与直形支架置入（血流速度保留率为43.0%-68.0%）不同，所有螺旋支架置入病例均显示血流速度得以维持（血流速度保留率为55.0%-71.3%）；然而，未观察到显著差异。
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