Lycheva T A, Petrovskaia V G
Zh Mikrobiol Epidemiol Immunobiol. 1979 Mar(3):63-6.
The loss of virulence was observed in some of the transconjugates of E. coli O124 in the process of the transfer of the plasmids differing in length: F' 200 PS, F'x 573 and F'x 363, carrying the genes of the chromosome area lac--pur E. The genetic determinants contributing to the ability of E. coli O124 to produce keratoconjunctivitis seem to be localized near the lactose marker, and not near E as in Sh. flexneri. In E. coli O124 these genetic determinants are probably localized on both sides of the lactose operon.
在转移长度不同的质粒(携带lac--pur E染色体区域基因的F' 200 PS、F'x 573和F'x 363)过程中,在一些大肠杆菌O124的转接合子中观察到了毒力丧失。导致大肠杆菌O124产生角膜结膜炎能力的遗传决定因素似乎位于乳糖标记附近,而不像弗氏志贺菌那样位于E附近。在大肠杆菌O124中,这些遗传决定因素可能位于乳糖操纵子的两侧。