Calbucci F, Tognetti F, Bollini C, Cuscini A, Michelucci R, Tassinari C A
Ital J Neurol Sci. 1986 Jun;7(3):359-66. doi: 10.1007/BF02340876.
Intracranial microvascular decompression was performed in 21 out of 24 patients with hyperactive dysfunction of cranial nerves: 8 cases of hemifacial spasm, 12 of trigeminal neuralgia, 3 of glossopharyngeal neuralgia and 1 case of paroxysmal vertigo and tinnitus. In 21 cases an abnormal vascular loop was found to impinge on the root entry zone of the nerve in the brainstem. Dissection of this loop with decompression of the nerve resulted in long-lasting relief of symptoms in all but two patients who presented early recurrence; in one of these a second procedure was eventually successful. In two patients with trigeminal neuralgia a benign tumor of the cerebellopontine angle that had escaped preoperative diagnosis was present. Finally, in one case no compressive lesions were found. From the data of the literature and from our present experience microvascular decompression can be considered a safe as well as an effective procedure, affording a high success rate in conditions often or usually resistant to medical treatment and erroneously considered "idiopathic".
24例颅神经功能亢进性功能障碍患者中有21例行颅内微血管减压术:8例面肌痉挛,12例三叉神经痛,3例舌咽神经痛,1例阵发性眩晕和耳鸣。21例中发现异常血管袢压迫脑干神经的神经根入区。将此血管袢分离并对神经进行减压后,除2例早期复发的患者外,所有患者症状均得到长期缓解;其中1例患者再次手术后最终成功。2例三叉神经痛患者存在术前未诊断出的桥小脑角良性肿瘤。最后,1例未发现压迫性病变。根据文献数据和我们目前的经验,微血管减压术可被认为是一种安全有效的手术,在通常或经常对药物治疗耐药且被错误地认为是“特发性”的疾病中成功率很高。