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经皮射频神经节溶解术与微血管减压术治疗三叉神经痛的手术疗效比较

Comparison of percutaneous radiofrequency gangliolysis and microvascular decompression for the surgical management of tic douloureux.

作者信息

Burchiel K J, Steege T D, Howe J F, Loeser J D

出版信息

Neurosurgery. 1981 Aug;9(2):111-9. doi: 10.1227/00006123-198108000-00001.

Abstract

Forty-two patients with tic douloureux underwent posterior fossa craniectomy and microvascular decompression (MVD) or partial rhizotomy of the trigeminal nerve and were followed an average of 25 months after operation. Thirty-six patients were found to have anatomical distortions of the nerve by an artery, vein, bony prominence, or a combination of factors, and 30 patients (83%) of this groups hav remained pain-free postoperatively. Six patients had no discernible pathological condition at the time of operation and underwent partial trigeminal rhizotomy. No patient underwent repeated MVD or rhizotomy, although 4 patients whose pain recurred after MVD underwent rhizotomy at a second operation. Eight of the 10 patients treated by rhizotomy are currently pain-free. The overall success rate of the entire group is 90%; 2% experienced a complication, and there was 1 perioperative death. Seventy-eight patients with tic douloureux who underwent 92 percutaneous radiofrequency trigeminal gangliolysis (PRTG) procedures were evaluated on average of 56 months postoperatively. Sixty-eight per cent of these patients when evaluated 1 year postoperatively were pain-free. However, only 35% of the PRTG procedures resulted in continued pain relief 5 years after operation. Twelve of the 78 patients (15%) required repeat gangliolysis because of recurrent tic pain. Considering all 78 patients treated with 92 PRTG procedures, 64% were pain-free at follow-up examination. PRTG was associated wtih an 8% risk of complications, which included anesthesia dolorosa, corneal anesthesia with keratitis, and significant facial paresthesias. Both PRTG and MVD have advantages. MVD should be considered because: (a) it attacks what is believed to be the primary etiology of tic douloureux, (b) the trigeminal nerve is preserved, (c) postoperative pain relief dose not depend upon the production of sensory deficit, and (d) it may have a greater potential for producing long-lasting pain relief. However, PRTG has other advantages: (a) it avoids the risks of craniectomy, (b) it is repeated easily if tic pain recurs, (c) morbidity is minimal and there is essentially no risk of mortality, and (d) it is much less expensive.

摘要

42例三叉神经痛患者接受了后颅窝颅骨切除术和微血管减压术(MVD)或三叉神经部分切断术,术后平均随访25个月。36例患者被发现神经因动脉、静脉、骨质隆起或多种因素组合而出现解剖结构扭曲,该组中有30例患者(83%)术后一直无疼痛。6例患者在手术时未发现明显病理状况,接受了三叉神经部分切断术。尽管有4例微血管减压术后疼痛复发的患者在第二次手术时接受了切断术,但没有患者接受重复的微血管减压术或切断术。接受切断术治疗的10例患者中有8例目前无疼痛。整个组的总体成功率为90%;2%出现了并发症,围手术期有1例死亡。78例接受了92次经皮射频三叉神经节溶解术(PRTG)的三叉神经痛患者术后平均随访56个月。这些患者术后1年评估时,68%无疼痛。然而,术后5年只有35%的经皮射频三叉神经节溶解术能持续缓解疼痛。78例患者中有12例(15%)因抽搐性疼痛复发需要重复神经节溶解术。考虑所有接受92次经皮射频三叉神经节溶解术治疗的78例患者,随访检查时64%无疼痛。经皮射频三叉神经节溶解术有8%的并发症风险,包括痛性麻木、角膜麻醉伴角膜炎和明显的面部感觉异常。经皮射频三叉神经节溶解术和微血管减压术都有优点。应考虑微血管减压术,原因如下:(a)它针对被认为是三叉神经痛的主要病因进行治疗;(b)保留三叉神经;(c)术后疼痛缓解不依赖于感觉缺失的产生;(d)它可能有更大的产生持久疼痛缓解的潜力。然而,经皮射频三叉神经节溶解术有其他优点:(a)它避免了颅骨切除术的风险;(b)如果抽搐性疼痛复发,很容易重复进行;(c)发病率极低,基本上没有死亡风险;(d)费用要低得多。

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