Michelucci R, Tassinari C A, Samoggia G, Tognetti F, Calbucci F
Ital J Neurol Sci. 1986 Jun;7(3):367-74. doi: 10.1007/BF02340877.
20 patients who had undergone microvascular decompression for the treatment of "idiopathic" trigeminal neuralgia (9 cases), hemifacial spasm (7 cases), glossopharyngeal neuralgia (3 cases) and paroxysmal vertigo and tinnitus (1 case) were followed up for 25 months on average. Permanent relief of symptoms was observed in 19 (95%), with sparing of cranial nerve function. Analysis of the clinical data shows that the patients described in the present series did not differ from those considered to suffer from "idiopathic" cranial nerve dysfunction syndromes. The importance of vascular cross compression as etiological factor in such conditions is stressed and the pathophysiology discussed. The term "cryptogenic" applied to trigeminal neuralgia or hemifacial spasm thus needs revising. Lastly, the indications of microvascular decompression in the treatment of "cryptogenic" cranial nerve dysfunction syndromes are defined.
对20例因“特发性”三叉神经痛(9例)、面肌痉挛(7例)、舌咽神经痛(3例)以及阵发性眩晕和耳鸣(1例)接受微血管减压术的患者进行了平均25个月的随访。19例(95%)患者症状得到永久性缓解,且保留了颅神经功能。临床数据分析表明,本系列所描述的患者与那些被认为患有“特发性”颅神经功能障碍综合征的患者并无差异。强调了血管交叉压迫作为此类病症病因的重要性并讨论了病理生理学。因此,应用于三叉神经痛或面肌痉挛的“隐源性”一词需要修订。最后,明确了微血管减压术在治疗“隐源性”颅神经功能障碍综合征中的适应证。