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经口内镜甲状腺切除术前庭入路作为一种新的技术用于儿科人群:单外科医生的经验。

Transoral endoscopic thyroidectomy vestibular approach as a novel technique for pediatric populations: Results from a single surgeon.

机构信息

Department of Head and Neck Surgery, Vietnam National Cancer Hospital, Hanoi, Vietnam.

Department of Oncology, Hanoi Medical University, Hanoi, Vietnam.

出版信息

Front Endocrinol (Lausanne). 2023 Jun 2;14:1177633. doi: 10.3389/fendo.2023.1177633. eCollection 2023.

Abstract

BACKGROUND

The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is increasingly being adopted worldwide because of its many advantages. However, there are few reports on the effectiveness and safety of TOETVA in children. In this study, we report the results of the application of TOETVA on 27 pediatric patients in Vietnam. To the best of our knowledge, this is also the largest sample size of the TOETVA technique performed by a single surgeon on pediatric patients worldwide. Patients and methods: From June 2020 to February 2022, we performed TOETVA on 27 pediatric patients (≤ 18 years old). The outcomes of the procedure were retrospectively reviewed.

RESULTS

Our study was conducted on 27 pediatric patients, of whom 24 were female (88.9%). The mean age was 16.3 ± 2 (range 10-18). Fifteen patients had benign thyroid nodules with a mean nodule size of 31.6 ± 7.1 (range 20-50mm), and 12 patients had papillary thyroid carcinoma with a mean nodule size of 10.2 ± 5.6 (range 4-19mm). All 27 patients underwent successful TOETVA without any conversion to open surgery. The 15 patients with benign thyroid nodules had lobectomies with a mean operative time of 83.3 ± 10.5 (range 60-105 minutes). Among the 12 patients diagnosed with thyroid cancer, ten had a lobectomy, isthmusectomy, and central neck dissection, with a mean operative time of 89.8 ± 5.7 (range 80-100 minutes). The other two underwent total thyroidectomy with central lymph node dissection with a mean operative time of 132.5 minutes. The mean hospital stay was 4.7 ± 0.9 (range 3-7 days). No patient had permanent complications, such as hypocalcemia, recurrent laryngeal nerve injury, or mental nerve injury. The rates of temporary recurrent laryngeal nerve injury and mental nerve injury were 3.7% and 11.1% respectively.

CONCLUSIONS

TOETVA may be a feasible and safe surgical method for children with thyroid disease. However, we recommend that only high-volume thyroid surgeons with experience in TOETVA should perform TOETVA on the pediatric population.

摘要

背景

经口内镜甲状腺手术(TOETVA)因其诸多优势在全球范围内得到越来越多的应用。然而,关于 TOETVA 在儿童中的有效性和安全性的报道较少。本研究报告了在越南 27 名儿科患者中应用 TOETVA 的结果。据我们所知,这也是由单一外科医生在全球范围内对儿科患者进行的 TOETVA 技术的最大样本量。

患者和方法

2020 年 6 月至 2022 年 2 月,我们对 27 名儿科患者(≤18 岁)进行了 TOETVA。回顾性分析了手术结果。

结果

本研究共纳入 27 名儿科患者,其中 24 例为女性(88.9%)。平均年龄为 16.3 ± 2 岁(10-18 岁)。15 例为良性甲状腺结节,平均结节大小为 31.6 ± 7.1mm(20-50mm),12 例为甲状腺乳头状癌,平均结节大小为 10.2 ± 5.6mm(4-19mm)。所有 27 例患者均成功施行 TOETVA,无中转开放手术。15 例良性甲状腺结节患者行甲状腺叶切除术,平均手术时间为 83.3 ± 10.5 分钟(60-105 分钟)。12 例甲状腺癌患者中,10 例行甲状腺叶切除术、峡部切除术和中央区淋巴结清扫术,平均手术时间为 89.8 ± 5.7 分钟(80-100 分钟);另外 2 例行甲状腺全切除术和中央区淋巴结清扫术,平均手术时间为 132.5 分钟。平均住院时间为 4.7 ± 0.9 天(3-7 天)。无患者发生永久性并发症,如低钙血症、喉返神经损伤或喉上神经损伤。暂时性喉返神经损伤和喉上神经损伤的发生率分别为 3.7%和 11.1%。

结论

TOETVA 可能是儿童甲状腺疾病的一种可行且安全的手术方法。然而,我们建议只有具有 TOETVA 经验的大容量甲状腺外科医生才应在儿科人群中施行 TOETVA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/011e/10272734/49f69b892383/fendo-14-1177633-g001.jpg

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