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睾酮与老年男性:来自发展中国家的观点。

Testosterone and aging male, a perspective from a developing country.

机构信息

Department of Andrology and Sexual Medicine, Hanoi Medical University's Hospital, Hanoi, Vietnam.

Department of Urology, Hanoi Medical University's Hospital, Hanoi, Vietnam.

出版信息

Aging Male. 2023 Dec;26(1):2223712. doi: 10.1080/13685538.2023.2223712.

Abstract

PURPOSE

Hypogonadism is associated with a wide range of physical and psychological symptoms that can affect the overall health of men. However, in a developing country, there are several imposing challenges in the diagnosis and treatment of hypogonadism, including a lack of awareness and understanding of the condition among healthcare providers and patients, limited resources and the high cost of treatment. This review aimed to examine the potential benefits and risks of testosterone replacement therapy (TRT) and provides a perspective of a developing country on the topic.

MATERIALS AND METHODS

A comprehensive literature review was conducted to gather relevant information on the impact of testosterone deficiency on ageing males and the effectiveness of TRT for treating hypogonadism. Published peer-reviewed articles were analyzed to evaluate the benefits and risks of TRT. Additionally, the unique challenges faced in the diagnosis and treatment of hypogonadism in a developing country were considered.

RESULTS

Testosterone replacement therapy has been shown to be an effective treatment for hypogonadism, particularly in symptomatic men with low testosterone levels. It offers potential benefits such as improvements in symptoms and overall quality of life. However, there are associated risks and side effects that need to be considered. In a developing country, challenges such as limited awareness and understanding of hypogonadism, resource constraints, and high treatment costs pose additional barriers to accessing TRT and comprehensive care.

CONCLUSION

In conclusion, TRT holds promise as a treatment for hypogonadism, but its implementation and accessibility face significant challenges in a developing country. Addressing these challenges, including raising awareness, allocating resources, and finding cost-effective solutions, is crucial for ensuring that men with hypogonadism in such settings receive appropriate diagnosis and treatment. Further research and efforts are needed to improve the management of hypogonadism in developing countries and optimize the potential benefits of TRT for affected individuals.

摘要

目的

性腺功能减退症与广泛的身体和心理症状相关,这些症状会影响男性的整体健康。然而,在发展中国家,性腺功能减退症的诊断和治疗存在一些严峻的挑战,包括医疗保健提供者和患者对该病症的认识和理解有限、资源有限以及治疗费用高昂。本综述旨在探讨睾酮替代疗法(TRT)的潜在益处和风险,并从发展中国家的角度探讨该主题。

材料与方法

进行了全面的文献综述,以收集有关睾酮缺乏对老年男性的影响以及 TRT 治疗性腺功能减退症的有效性的相关信息。分析已发表的同行评议文章,以评估 TRT 的益处和风险。此外,还考虑了发展中国家在诊断和治疗性腺功能减退症方面面临的独特挑战。

结果

TRT 已被证明是治疗性腺功能减退症的有效方法,特别是对低睾酮水平且有症状的男性。它具有改善症状和整体生活质量的潜在益处。然而,需要考虑与之相关的风险和副作用。在发展中国家,性腺功能减退症的认识和理解有限、资源有限以及治疗费用高昂等挑战,对获得 TRT 和全面治疗构成了额外的障碍。

结论

总之,TRT 作为治疗性腺功能减退症的方法具有一定的前景,但在发展中国家实施和获得该治疗方法面临着重大挑战。解决这些挑战,包括提高认识、分配资源和寻找具有成本效益的解决方案,对于确保在这些环境中患有性腺功能减退症的男性得到适当的诊断和治疗至关重要。需要进一步的研究和努力来改善发展中国家的性腺功能减退症管理,并优化 TRT 对受影响个体的潜在益处。

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