来自东方诺卡氏菌NRRL 2452（一种万古霉素产生菌）的隐蔽质粒。

A cryptic plasmid from Nocardia orientalis NRRL 2452, a vancomycin producer.

作者信息

Oh Y K, Fare L R, Taylor D P, Widger J, Nisbet L J

出版信息

J Antibiot (Tokyo). 1986 May;39(5):694-8. doi: 10.7164/antibiotics.39.694.

DOI:10.7164/antibiotics.39.694

Abstract

A plasmid was found in Nocardia orientalis (formerly Streptomyces orientalis). Physical characterization of the plasmid DNA indicates a size of 33.5 kb and a single cleavage site for EcoR I. The presence of plasmid, and variation in its copy member, did not directly affect vancomycin resistance or production levels. The plasmid represents the first to be isolated and characterized from a glycopeptide-producing nocardia.

摘要

在东方诺卡氏菌（以前称为东方链霉菌）中发现了一种质粒。质粒DNA的物理特性表明其大小为33.5 kb，且有一个EcoR I的单一切割位点。质粒的存在及其拷贝数的变化并未直接影响万古霉素抗性或产量水平。该质粒是从产生糖肽的诺卡氏菌中分离并鉴定的首个质粒。