基底膜振动的测量与耳蜗状况的评估。

Measurement of basilar membrane vibrations and evaluation of the cochlear condition.

作者信息

Khanna S M, Leonard D G

出版信息

Hear Res. 1986;23(1):37-53. doi: 10.1016/0378-5955(86)90174-7.

Abstract

The experimental procedure for measuring basilar membrane responses to acoustic signals is described. The surgical procedure developed for opening the cochlea with minimal trauma is presented. Each experiment included sound pressure level measurements to define the input signal, cochlear microphonic (CM) measurements to monitor the cochlear condition, interferometric measurements and histological evaluation of the cochleas. The characteristic frequency (CF) and the sensitivity at CF for the basilar membrane response is correlated with the change of CM response observed in six animals. It is demonstrated that both tuning characteristics are extremely sensitive to cochlear trauma as evidenced by changes of CM.

摘要

描述了测量基底膜对声信号反应的实验程序。介绍了为在最小创伤下打开耳蜗而开发的手术程序。每个实验都包括用于定义输入信号的声压级测量、用于监测耳蜗状况的耳蜗微音电位（CM）测量、干涉测量以及耳蜗的组织学评估。在六只动物中观察到基底膜反应的特征频率（CF）和CF处的灵敏度与CM反应的变化相关。结果表明，如CM变化所示，这两种调谐特性对耳蜗创伤都极其敏感。