Department of Movement Sciences, KU Leuven, Movement Control and Neuroplasticity Research Group, Leuven, Belgium.
KU Leuven, Leuven Brain Institute, Department of Movement Sciences, Movement control & Neuroplasticity Research Group, Leuven, Belgium.
J Mot Behav. 2023;55(5):525-537. doi: 10.1080/00222895.2023.2221985. Epub 2023 Jun 19.
The characterization of callosal white matter is crucial for understanding the relationship between brain structure and bimanual motor function. An earlier literature review established this. With advancements in neuroimaging and data modeling, we aim to provide an update on the existing literature. Firstly, we highlight new CC parcellation approaches, such as functional MRI- and atlas-informed tractography and in vivo histology. Secondly, we elaborate on recent insights into the CC's role in bimanual coordination, drawing evidence from studies on healthy young and older adults, patients and training-related callosal plasticity. We also reflect on progress in the field and propose future perspectives to inspire research on the underlying mechanisms of structural-functional interactions.
胼胝体白质的特征对于理解大脑结构和双手运动功能之间的关系至关重要。这一点在早期的文献综述中已经得到了证实。随着神经影像学和数据建模技术的进步，我们旨在提供该领域现有文献的最新更新。首先，我们强调新的胼胝体分割方法，如基于功能磁共振成像和图谱的示踪技术以及活体组织学方法。其次，我们详细阐述了胼胝体在双手协调中的作用的最新研究进展，这些研究结果来自于对健康年轻和老年成年人、患者以及与训练相关的胼胝体可塑性的研究。我们还反思了该领域的进展，并提出了未来的展望，以激发对结构-功能相互作用的潜在机制的研究。
